DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ndf and GLYR2

DIOPT Version :9

Sequence 1:	NP_001188767.1	Gene:	Ndf / 192507	FlyBaseID:	FBgn0043456	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_564030.2	Gene:	GLYR2 / 838342	AraportID:	AT1G17650	Length:	358	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	106/314 - (33%)
Similarity:	177/314 - (56%)	Gaps:	6/314 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 PVVTRPE---AQVIDMSSRSNTLADRDIVPSEQTFGFLGLGMMGSTIVKDLIYTGHKVVVWNRTI 348
            |.:::|:   |..:..|.:|.|.:.||.: ...:.||||:|:|||.:.::||..|..|.|||||.
plant    36 PFLSKPQICLAYRVYSSLQSTTPSTRDEL-GTVSIGFLGMGIMGSPMAQNLIKAGCDVTVWNRTK 99

  Fly   349 DKCQPFAEAGAEVKDTPMDVVEAADVIFCCVSDPKGAKDLVFGNCGVLQLKDLNNKAYVEMSTID 413
            .||.|....||:.|.:|.:|....|:.|..::||:.|.|:..|..|.: ....:.|.||::||:|
plant   100 SKCDPLVGLGAKYKSSPEEVTATCDLTFAMLADPESAIDVACGKNGAI-FGISSGKGYVDVSTVD 163

  Fly   414 PDTSLDIGEGIKQCNGRYLEAQIHGSRQEAAEGMLIILAGGDRSVFEECHSCFKTIAKNTFFLGT 478
            ..:|:.|.:.||.....:|||.:.||::.|.:|.||.|..||:.::|:.......:.|:.|:||
plant   164 VASSILISKQIKDTGALFLEAPVSGSKKPAEDGQLIFLTAGDKPLYEKAAPFLDIMGKSKFYLG- 227

  Fly   479 DIGNACKVNLILQTILGVSLVGLAEALALADRFSISLNDIIDIFDLTSMKSPMLLAKGKEMAKGD 543
            ::||...:.|::..|:|..:...||.:.|:.:..:..|.::::....::.:||...||..|.|..
plant   228 EVGNGAAMKLVVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVSQGAINAPMYSLKGPSMIKSV 292

  Fly   544 FNPQQPLSHMQRDLRLVLNMAENLDQSMPVTSITNEVFKHTKRLGYSEHDSSAV 597
            :....||.|.|:|:||.|.:||::.||.|:.:..||::|..|..|.|:.|.|||
plant   293 YPTAFPLKHQQKDMRLALGLAESVSQSTPIAAAANELYKVAKSYGLSDEDFSAV 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndf	NP_001188767.1	N_Pac_NP60	20..106	CDD:99897
		NAD_binding_2	316..477	CDD:281445	58/160 (36%)
		MmsB	319..597	CDD:224995	96/277 (35%)
		NAD_binding_11	481..597	CDD:291499	36/115 (31%)
GLYR2	NP_564030.2	MmsB	68..351	CDD:224995	98/281 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1647
eggNOG	1	0.900	-	-		E1_COG2084
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	200	1.000	Inparanoid score	I1319
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002426
OrthoInspector	1	1.000	-	-		otm2856
orthoMCL	1	0.900	-	-		OOG6_100977
Panther	1	1.100	-	-	O	PTHR43580
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4119
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.820