Protein Alignment Ndf and glyr1

DIOPT Version :10

• Sequence 1: NP_001188767.1
• Gene: Ndf / 192507
• FlyBaseID: FBgn0043456
• Length: 603
• Species: Drosophila melanogaster
• Sequence 2: NP_001025665.1
• Gene: glyr1 / 595057
• XenbaseID: XB-GENE-958848
• Length: 534
• Species: Xenopus tropicalis
• Alignment Length: 608
• Identity: 202/608 - (33%)
• Similarity: 304/608 - (50%)
• Gaps: 121/608 - (19%)

  Fly    24 DLIWAKMKGFTPWPGMIVDPPLDLLSQQRRANTKCVF--FFGSRNFAWIEENNIKPFEGPWKEEL 86
            ||:|.|:..:.||||.||:||.||   ::....||:|  |||:.:.|||:...:||:.. .|||:
 Frog    10 DLVWGKLGRYPPWPGKIVNPPKDL---KKPRGKKCLFVKFFGTEDHAWIKVEQLKPYHA-HKEEM 70

  Fly    87 AKVSKPAAFRHAMTDIEKYIDDPAEVDEQVNKSCGAPNHATEADFDKIRDGLDSEEIVGEEATAD 151
            .|.:|...|:.|:..:|:::           |...|..||.|.:        .|:|
 Frog    71 IKANKGKRFQQAVDAVEEFL-----------KKAKAKEHAKEHN--------SSDE--------- 107

  Fly   152 GNNGVVAHVVGSPDEGDGLDVEINADSSASPVTSPAVTTKAAGKRTPKAKSVAATSVKSTKGSAK 216
                     .|...||.|                    .|..|::..          ||::.|:.
 Frog   108 ---------KGKKGEGKG--------------------KKQTGEKRR----------KSSESSSH 133

  Fly   217 SAQKRRTSAQQSPSGPSNAKRGK--RDVSGEALQDADEASSTPTGRRRV-------------ETD 266
            |.|||  |..|||     .|||:  :|       |.|..|..|:..:::             .|:
 Frog   134 SPQKR--SRDQSP-----RKRGRPPKD-------DKDSPSPQPSSLKKLAMKTVSRFSWPPPSTE 184

  Fly   267 ALLAS----IAAKRAPNAIALLDRPVVT------RPEAQVIDMSSRSNTLADR-----DIVPSEQ 316
            ..|.|    |...|......:|.:|.||      |.:....|..|.|...||.     :|:|:::
 Frog   185 DDLGSDSWLIHGHRTLGTEMILKKPSVTYQAITKRLKISEEDSGSTSIQAADSTAINGNIIPTDK 249

  Fly   317 TFGFLGLGMMGSTIVKDLIYTGHKVVVWNRTIDKCQPFAEAGAEVKDTPMDVVEAADVIFCCVSD 381
            ..||||||:|||.||.:|:..||.|.|||||.:||..|.:.||.:..||.:||...|:.|.||:|
 Frog   250 KIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAHMGRTPAEVVSTCDITFACVAD 314

  Fly   382 PKGAKDLVFGNCGVLQ-LKDLNNKAYVEMSTIDPDTSLDIGEGIKQCNGRYLEAQIHGSRQEAAE 445
            ||.|||||.|..|||| ::.  .|.||:|||:||:|..::.:.|....||:|||.:.|::|.:.:
 Frog   315 PKAAKDLVLGPSGVLQGIRP--GKCYVDMSTVDPETVAELAQVIVSRGGRFLEAPVSGNQQLSND 377

  Fly   446 GMLIILAGGDRSVFEECHSCFKTIAKNTFFLGTDIGNACKVNLILQTILGVSLVGLAEALALADR 510
            |||:|||.||:.|:|:|.|||..:.|.:|||| ::|||.::.|||..:.|..:..:||.:.||..
 Frog   378 GMLVILAAGDQGVYEDCSSCFLAMGKTSFFLG-EVGNAARMMLILNMVQGSFMATIAEGMTLAQV 441

  Fly   511 FSISLNDIIDIFDLTSMKSPMLLAKGKEMAKGDFNPQQPLSHMQRDLRLVLNMAENLDQSMPVTS 575
            ...|...::||.:...:.|..|..|.:.:.:|:|.|...|.::|:||||.:.:.::::...|:.:
 Frog   442 TGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDSVNHPTPMAA 506

  Fly   576 ITNEVFKHTKRLGYSEHDSSAVF 598
            ..|||:|..|.|..|::|.|||:
 Frog   507 AANEVYKRAKALDQSDNDMSAVY 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndf	NP_001188767.1	PWWP_GLYR1	20..106	CDD:438961	33/83 (40%)
		MmsB	319..598	CDD:441687	119/279 (43%)
glyr1	NP_001025665.1	PWWP_GLYR1	9..90	CDD:438961	33/83 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..168		31/144 (22%)
		Interaction with histone H3. /evidence=ECO:0000250|UniProtKB:Q49A26	190..193		0/2 (0%)
		Dehydrogenase domain. /evidence=ECO:0000250|UniProtKB:Q49A26	242..534		122/291 (42%)
		MmsB	249..532	CDD:441687	120/284 (42%)