DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ndf and psip1a

DIOPT Version :9

Sequence 1:	NP_001188767.1	Gene:	Ndf / 192507	FlyBaseID:	FBgn0043456	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_009289823.1	Gene:	psip1a / 553760	ZFINID:	ZDB-GENE-050522-104	Length:	417	Species:	Danio rerio

Alignment Length:	441	Identity:	102/441 - (23%)
Similarity:	170/441 - (38%)	Gaps:	87/441 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 YKPKDLIWAKMKGFTPWPGMIVDPPLDLLSQQRRANTKC-VFFFGSRNFAWIEENNIKPFEGPWK 83
            :|..|||:|||||:..||..|.:.|...:   :.:|.|. :||||:...|::...:|.|:... |
Zfish     5 FKAGDLIFAKMKGYPHWPARIDEIPDGAV---KPSNIKFPIFFFGTHETAFLGPKDIFPYLTN-K 65

  Fly    84 EELAKVSKPAAFRHAMTDIEKYIDDPAEVDEQVNKSCGAPNHATEADFDKIRDGLDSEEIVGEEA 148
            ::..|.:|...|...:.:||.  :...|::....|..|..:         |:|...:||...|:.
Zfish    66 DKYGKPNKRKGFNEGLWEIEN--NPKVELNGHKVKKVGEVS---------IKDLSSNEEGDDEKR 119

  Fly   149 TADGNNGVVAHVVGSPDE-----GDGLDVEIN-----ADSSASPVTSPAVTTKAAGKRTPKAKSV 203
            |   .:..:||..|..||     .||.|::::     .|...|...|..||.||  ||..|.||.
Zfish   120 T---KSAQIAHSEGLEDEVDIEKEDGGDMDVSDQRLVKDEDLSQKDSTNVTAKA--KRGRKRKSD 179

  Fly   204 A-----------------------ATSVKSTKGSAKSAQKRRT---SAQQSPSGPSNAKRGKRDV 242
            |                       .||:...|...:.::..::   ..|.|...|.:.|.||||.
Zfish   180 AEQDSDTENSSPTAGGSGLDFLSTGTSIMLLKRRGRKSKTEKSIILQQQASKELPRSGKDGKRDE 244

  Fly   243 -SGEALQDADEASSTPTGRRRVETDALLASIAAKRAPNAIALLDRPVVTRPEAQ----------V 296
             .|:..::....|:.......::|...:.::..::..:|:..|....||....|          .
Zfish   245 RKGDKRKEVSAESTLQKLHGEIKTSLKIGNLDVRKCVHALDELSSLHVTTQHLQRHSELIATLKK 309

  Fly   297 IDMSSRSNTLADRDIVPSEQTFGFLGLGMMGSTIVKDLIYTGHKVV--VWNRTIDKCQPFAEAGA 359
            |.....|..:.|:.|:...:   |..:.:||.         |..|:  |.|:::.:.:.|.||..
Zfish   310 ICRFKSSQDVMDKAIMLYNK---FKSMFLMGE---------GESVLSQVLNKSLTEQKLFEEAKR 362

  Fly   360 EVKDTPMDVVEAADV-----IFCCVSDPKGAKDLVFGNCGVLQLKDLNNKA 405
            .|........|..|.     .|....|.:..||.:.||...:...::.|.|
Zfish   363 GVLKNTEQTKEQKDTKILNEDFNSEEDAETEKDKLGGNILSMVKNNMTNPA 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndf	NP_001188767.1	N_Pac_NP60	20..106	CDD:99897	28/86 (33%)
		NAD_binding_2	316..477	CDD:281445	21/97 (22%)
		MmsB	319..597	CDD:224995	21/94 (22%)
		NAD_binding_11	481..597	CDD:291499
psip1a	XP_009289823.1	HDGF_related	3..87	CDD:99895	28/87 (32%)
		FRQ	<104..195	CDD:286504	27/104 (26%)
		LEDGF	256..357	CDD:288344	18/112 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910