DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ndf and hdgfl2

DIOPT Version :9

Sequence 1:	NP_001188767.1	Gene:	Ndf / 192507	FlyBaseID:	FBgn0043456	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_031753048.1	Gene:	hdgfl2 / 394783	XenbaseID:	XB-GENE-6456056	Length:	678	Species:	Xenopus tropicalis

Alignment Length:	269	Identity:	69/269 - (25%)
Similarity:	99/269 - (36%)	Gaps:	76/269 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SGGD----TTEKFIYKPKDLIWAKMKGFTPWPGMI-------VDPPLDLLSQQRRANTKCVFFFG 63
            |.||    .|....:||.||::|||||:..||..|       |.||         .|...:||:|
Frog    27 SRGDPNRTVTMPLNFKPGDLVFAKMKGYPHWPARIDDVKDGAVKPP---------PNKYPIFFYG 82

  Fly    64 SRNFAWIEENNIKPFEGPWKEELAKVSKPAAFRHAMTDIE-----KYIDDPAEVDEQVNKSCGAP 123
            :...|::...::.|:| ..|::..|.:|...|...:.:|:     .|...||.|.   :.....|
Frog    83 THETAFLAPKDLFPYE-KCKDKYGKPNKRKGFNEGLWEIQNNPQASYSLPPASVS---SSDSDVP 143

  Fly   124 NHATEADFDKIRDGLDSEEIVGEEATADGNNGVVAHVVGSPDEGDGLDVEINADSSASPVTSPAV 188
            ...:.|..|            |||....|...:....|.|.|| :|.|
Frog   144 EEKSTARSD------------GEEEQETGQAILPTAGVSSSDE-EGSD----------------- 178

  Fly   189 TTKAAGKRTPKAKSVAATSVKSTKGSAKSAQKRRTSAQQSPSGPSNAKRGKRDVSGEALQDADEA 253
              |...||  |.::....|.|.||.|         |::|.|...|:::....|..    ||....
Frog   179 --KGGVKR--KGRTTTPPSAKRTKHS---------SSEQEPDSASSSEEENSDSD----QDFTPE 226

  Fly   254 SSTPTGRRR 262
            .|||..:||
Frog   227 KSTPRIQRR 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndf	NP_001188767.1	N_Pac_NP60	20..106	CDD:99897	27/97 (28%)
		NAD_binding_2	316..477	CDD:281445
		MmsB	319..597	CDD:224995
		NAD_binding_11	481..597	CDD:291499
hdgfl2	XP_031753048.1	HDGF_related	40..123	CDD:99895	27/92 (29%)
hdgfl2	XP_031753048.1	LEDGF	500..590	CDD:402877
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910