DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ndf and Hdgfl2

DIOPT Version :9

Sequence 1:	NP_001188767.1	Gene:	Ndf / 192507	FlyBaseID:	FBgn0043456	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	XP_006244351.1	Gene:	Hdgfl2 / 171073	RGDID:	621013	Length:	678	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	80/313 - (25%)
Similarity:	129/313 - (41%)	Gaps:	59/313 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 YKPKDLIWAKMKGFTPWPGMI-------VDPPLDLLSQQRRANTKCVFFFGSRNFAWIEENNIKP 77
            :||.||::|||||:..||..|       |.||         .|...:||||:...|::...::.|
  Rat     5 FKPGDLVFAKMKGYPHWPARIDDIADGAVKPP---------PNKYPIFFFGTHETAFLGPKDLFP 60

  Fly    78 FEGPWKEELAKVSKPAAFRHAMTDIEKYIDDPAEVDEQVNKSCGAP-------NHATEADFDKIR 135
            :: ..|::..|.:|...|...:.:|:   ::|       :.|..||       :.|.|||.....
  Rat    61 YD-KCKDKYGKPNKRKGFNEGLWEIQ---NNP-------HASYSAPLPVSSSDSEAPEADLGGGS 114

  Fly   136 DGLDSEEIVGEEATADGNNGVVAHVVGSPDEGDGLDVEINADSSASPVTSPAVTTKAAGKRTPKA 200
            |. |.|:......|.   ..|.........|.|. |.:.|:|.|.....:| |...:..||..||
  Rat   115 DA-DKEKEARRVMTV---TAVTTTATSGRTESDS-DSDKNSDHSGLKRKTP-VLKMSVSKRARKA 173

  Fly   201 KS-VAATSVK-STKGSAKSAQKRRTSAQQ-SPSGPSNAKRGKRDVSGEALQDADEASSTPTGRRR 262
            .| :...||. |.:.|...::..:||.|. :|...:.|:..:|...|...:.....|:.|   ::
  Rat   174 SSDLDQASVSPSEEDSESPSESEKTSDQDFTPEKKTIARAPRRAPLGGRKKKQPTGSACP---QK 235

  Fly   263 V----ETDALLASIAAKRAPNAIALLDRPVVTRPEAQVIDMSSRSNTLADRDI 311
            |    ::|:...|..||         :.||||...:.....||.|::.:|.|:
  Rat   236 VPSASDSDSRADSDGAK---------EEPVVTAQPSPSSSSSSSSSSASDSDV 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndf	NP_001188767.1	N_Pac_NP60	20..106	CDD:99897	27/92 (29%)
		NAD_binding_2	316..477	CDD:281445
		MmsB	319..597	CDD:224995
		NAD_binding_11	481..597	CDD:291499
Hdgfl2	XP_006244351.1	HDGF_related	3..87	CDD:99895	27/94 (29%)
Hdgfl2	XP_006244351.1	LEDGF	477..561	CDD:288344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910