Protein Alignment Ptpn12 and CG42327

DIOPT Version :10

• Sequence 1: NP_001343519.1
• Gene: Ptpn12 / 19248
• MGIID: 104673
• Length: 789
• Species: Mus musculus
• Sequence 2: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Alignment Length: 296
• Identity: 86/296 - (29%)
• Similarity: 138/296 - (46%)
• Gaps: 66/296 - (22%)

Mouse    75 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVY-GPKAYVATQGPLANTVIDFWRMIWEY 138
            ||||.:::|...:||.|..:.....::|||||:::|.. .|..|:|.|.||.:|..||||||||.
  Fly  1135 KNRYANVIPLPETRVVLQRQGDDDKTEYINANYVRGPRDAPNYYIACQAPLESTTSDFWRMIWEQ 1199

Mouse   139 NVVIIVMACREFEMGRKKCERYWPLYG--EDPITFAPFKISCENEQARTDYFIRTLLLEFQN--E 199
            ...:|:.|....|.|.::|..|.|...  ::..::..::::.::.:.:..|.|.||:|:..:  |
  Fly  1200 QSRVIIQATDLSENGIERCAEYLPPSATLDNHSSYGDYQVTLKHREVKDRYAISTLVLKRVDGEE 1264

Mouse   200 SRRLYQFHYVNWPDHDVPSSFDSILDMI----SLMRKY--------------------------- 233
            ||.|..:.| .||:..||:....|:.|:    |.::.|
  Fly  1265 SRELTHYWY-KWPEAGVPAEEAPIIAMLLEARSSLKSYSLEQANELREKSATLETSMDADGSKAE 1328

Mouse   234 ----QEHE--------------DVPICIHCSAGCGRTGAICAIDYTWNLLKAGK----IPEEFNV 276
                ..||              ..|:.:|||.|.||||.|.|.|.....|:..|    ||:
  Fly  1329 AGSTSSHEINGNISSRSGTRSQQGPLTVHCSPGTGRTGTIIASDMAIRSLETPKRSVDIPQ---- 1389

Mouse   277 FNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQL 312
              |:..:|..|.||||||||||.::: :|.::..::
  Fly  1390 --LVYYVRRGRASAVQTKEQYEFIYK-VASMYAAKI 1422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpn12	NP_001343519.1	PTP_DSP_cys	43..312	CDD:475123	86/294 (29%)
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:214550	85/287 (30%)