Protein Alignment Ptpn12 and PTP-ER

DIOPT Version :9

• Sequence 1: NP_001343519.1
• Gene: Ptpn12 / 19248
• MGIID: 104673
• Length: 789
• Species: Mus musculus
• Sequence 2: NP_726092.1
• Gene: PTP-ER / 37461
• FlyBaseID: FBgn0016641
• Length: 1377
• Species: Drosophila melanogaster
• Alignment Length: 458
• Identity: 110/458 - (24%)
• Similarity: 157/458 - (34%)
• Gaps: 219/458 - (47%)

Mouse    75 KNRYKDILPFDHSRVKLTLK-----------------TPSQDSDYINANFIKGV-YGPKAYVATQ 121
            |||||.|||.::|||.|..:                 |.|:|..|||||:|||. |..|.|||||
  Fly   918 KNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQ 982

Mouse   122 GPLANTVIDFWRMIWEYN---------------------------VVIIVMACREFEMGRKKCER 159
            |||.||:.:||.||::..                           ...|||.....|..|:||..
  Fly   983 GPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAV 1047

Mouse   160 YWPL-----------------------YGEDPI--TFAP-----------------------FKI 176
            |:|:                       |.:..:  ||.|                       .|:
  Fly  1048 YFPIELNEIFAVAAKCEVFQLSAAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKV 1112

Mouse   177 SCENE-------------------QARTDYFIRTLLLEF-----QNES---RRLYQFH--YVNWP 212
            :.|.:                   ..|..|.:|.|:|.:     |:.|   :::|.:|  |.:||
  Fly  1113 TLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHLQKIYCYHYWYPDWP 1177

Mouse   213 DHDVPSSFDSILD----MISL-------------------------MRKYQEH-----EDVPICI 243
            ||..|...:::||    :::|                         :..||:.     :.:|: |
  Fly  1178 DHHSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPV-I 1241

Mouse   244 HCSAGCGRTGAICAI---------------------------------------DYTWNLLK--- 266
            |||||.||||...||                                       .:|.|.::
  Fly  1242 HCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHIS 1306

Mouse   267 ---------AGKIPEEF-----------NVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQ 311
                     |.|.|..|           :|..::..:|.||...||..|||||:||||....::.
  Fly  1307 HILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT 1371

Mouse   312 LQL 314
            |.|
  Fly  1372 LAL 1374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpn12	NP_001343519.1	PTP_DSP_cys	43..312	CDD:391942	108/454 (24%)
PTP-ER	NP_726092.1	Y_phosphatase	916..1364	CDD:278528	106/446 (24%)
		PTPc	917..1364	CDD:238006	106/446 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0789
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900