DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptgs1 and cysu

DIOPT Version :9

Sequence 1:	NP_032995.1	Gene:	Ptgs1 / 19224	MGIID:	97797	Length:	602	Species:	Mus musculus
Sequence 2:	NP_650627.1	Gene:	cysu / 42100	FlyBaseID:	FBgn0038511	Length:	753	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	72/346 - (20%)
Similarity:	130/346 - (37%)	Gaps:	87/346 - (25%)

- Green bases have known domain annotations that are detailed below.

Mouse   300 LMLFSTIWLREHNRVCDLLKEEHPTWDDEQLFQTTRLILIGETIKIVIEEYVQHLSGYFLQLKF- 363
            |....|:..|||||:...|.:.:..||||.|||..|.|.|.....:...|::..|.|..:..||
  Fly   388 LTCMHTLMAREHNRLATALAQINKHWDDETLFQEARRINIAIVQHVTFNEFLPILLGKEVMEKFG 452

Mouse   364 ----------------DPELL---FRAQFQYRNRIAMEFNHLYHWHPLMPNSFQVGSQEYSY--- 406
                            :|.::   ..|.|::             .|.|:|.:.:..|:.:.:
  Fly   453 LVLQKDGYWDGYDSTVNPGIIDSFAGAAFRF-------------GHSLLPTAVERWSKAHKFIAS 504

Mouse   407 ---------EQFLFNTSMLVDYGV-------EALVDAFSRQRAGRIGGGRNFDYHVLHVAVDVI- 454
                     ...|:...:|.:|.:       :|:.|:.:::....:     |........:|::
  Fly   505 KRLSDLIRRPYDLYRAGVLDEYFMGLMNQVAQAMDDSITQEVTNHL-----FKKEGARFGMDLVS 564

Mouse   455 ---KESREMRLQPFNEYRKRFGLKPYTSFQELTGEKEMAAELEELYGDI----DALEFYPGLLLE 512
               :..||..:..:.|:||..||....::.|:.|  .|..|....||.|    ..::.:.|.:.|
  Fly   565 FNMQRGREFGIPGYMEFRKFCGLPTSNTWDEMYG--SMPNETVLRYGSIFEHPADIDLWSGGVSE 627

Mouse   513 KCQPNSIFGES---MIEMGAPFSLKGLLGNPICSPEYW-----KPSTFGGDVGFNLVNTASLKKL 569
            |..|.|:.|.:   :|.....:..:|        ..:|     :||:|..: ....:..|.|.:|
  Fly   628 KSLPGSMLGPTFACVIATQMSYLRRG--------DRFWYELPNQPSSFTPE-QLQEIRKAKLSRL 683

Mouse   570 VCLNT---KTCPYVSFRVPDY 587
            :|.||   .|.......:||:
  Fly   684 ICDNTDLIDTVQIYPMVLPDH 704

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptgs1	NP_032995.1	EGF_CA	35..72	CDD:238011
Ptgs1	NP_032995.1	prostaglandin_endoperoxide_synthase	92..578	CDD:188648	70/335 (21%)
cysu	NP_650627.1	An_peroxidase	155..692	CDD:281139	69/332 (21%)
cysu	NP_650627.1	peroxinectin_like	305..687	CDD:188655	67/327 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810