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Protein Alignment Ptgis and Cyp28a5

DIOPT Version :9

Sequence 1:	NP_032994.1	Gene:	Ptgis / 19223	MGIID:	1097156	Length:	501	Species:	Mus musculus
Sequence 2:	NP_609694.1	Gene:	Cyp28a5 / 34817	FlyBaseID:	FBgn0028940	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	559	Identity:	111/559 - (19%)
Similarity:	207/559 - (37%)	Gaps:	150/559 - (26%)

- Green bases have known domain annotations that are detailed below.

Mouse     6 LLGLLAVLLLLLLLLS----RRRARRPGEPPLDLGSIPWL----GHALEFGRDAASFLTRMKEKH 62
            |:.|:..||..:|:.:    |:|.....:|.|..|:.|.:    .||:   .|......:.|.|:
  Fly     8 LVSLVVGLLYAVLVWNYDYWRKRGVPGPKPKLLCGNYPNMFTMKRHAI---YDLDDIYRQYKNKY 69

Mouse    63 GDIFTVLVGGRYVTVLLDPHSYDTVVWELRTRLDFHPYAIFLMERIFDLQLPNFNPSEEKARMKP 127
            ..:  .:.|.|...:|:                 .:|   .|..|:|.....||:.:|
  Fly    70 DAV--GIFGSRSPQLLV-----------------INP---ALARRVFVSNFKNFHDNE------- 105

Mouse   128 TLMHRDLQALTEAMYTNLRTVLLGDSTEAGSGWQETGLLEFSYNALLSAGYL-TLY--------- 182
              :.:::...|:.::.|....|.|:..:........|         |:.|.: |:|
  Fly   106 --IAKNIDEKTDFIFANNPFSLTGEKWKTRRADVTPG---------LTMGRIKTVYPVTNKVCQK 159

Mouse   183 ---GVEASPRTHESQAQDRVHSADVFHTFRQLDLLLPKLARGSLSAGDKDHACSVK-----NRLW 239
               .||...|.......|..|.:..|.|....|.:   |..|:.|..||......|     |:.|
  Fly   160 LTEWVEKQLRLGSKDGIDAKHMSLCFTTEMVTDCV---LGLGAESFSDKPTPIMSKINDLFNQPW 221

Mouse   240 KLL---------------------------------------SPARLAS--RADRSSWLESYLRH 263
            ..:                                       ..|:||:  :.:||.:|:    :
  Fly   222 TFVLFFILTSSFPSLSHLIKLRFVPVDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLD----Y 282

Mouse   264 LEEMGVSEEMQARALV----------LQLWATQGNMGPTAFWLLLFLLKNPEALAAVRAELKHTV 318
            :.::|....:..|.|:          .:..||      ....:||.|.:|.||...:|.|::..:
  Fly   283 ILQLGEKRNLDNRQLLAYSMTFLLDGFETTAT------VLAHILLNLGRNKEAQNLLREEIRSHL 341

Mouse   319 WQAEQPVSQMTTLPQKILDSMPVLDSVLNETLRLTAAPFITREVMAD-LALPMADGREFSLRRGD 382
                    |..|:..:.|..:|.||:.:.||:||....|::.::..: :.:|..:|..|.:.:|.
  Fly   342 --------QDGTIAFEKLSDLPYLDACVQETIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGT 398

Mouse   383 RLLLFPFLSPQKDPEIYTEPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNQCLGKSY 447
            .::: |......|.|.:..|:.|:..|||.||.:  |.|     |.:...|.:|.|...|:|..:
  Fly   399 TVVV-PHYCFMLDEEFFPNPQSFQPERFLEPDAA--KTF-----RERGVFMGFGDGPRVCIGMRF 455

Mouse   448 AINSIKQFVVLLLTHFDLELGSEDTEVPEFDLSRYGFGL 486
            |...||..:|.|::.|::::..:..:..:::..:...||
  Fly   456 ATVQIKAAIVELISKFNVKINDKTRKDNDYEPGQIITGL 494

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.