Protein Alignment Ptger4 and CG7497

DIOPT Version :10

• Sequence 1: NP_032991.1
• Gene: Ptger4 / 19219
• MGIID: 104311
• Length: 513
• Species: Mus musculus
• Sequence 2: NP_648999.2
• Gene: CG7497 / 39966
• FlyBaseID: FBgn0036742
• Length: 412
• Species: Drosophila melanogaster
• Alignment Length: 446
• Identity: 104/446 - (23%)
• Similarity: 176/446 - (39%)
• Gaps: 117/446 - (26%)

Mouse    22 TTTIMSI--PGVNASFSSTPERL---NSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYT 81
            ||.::.:  |. |::..:.|:.|   .:.:.|..::.:.||.||.:|:.:|  :||:..:.:.||
  Fly     4 TTPVLDLLMPH-NSTTVAPPKALYANRNRLIIGVIIMVLGVFGNSLALFIL--ARKKLNKNSKYT 65

Mouse    82 LVCGLAVTD----LLG----TLL---VSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSII 135
            |:.....|:    |||    |||   :|...:.::::....|        ..:..|||||...|.
  Fly    66 LMLRCLATNNLVALLGMLTTTLLKMYLSKEVLQSFIRVDCVG--------LVVWRFFGLSSGCIA 122

Mouse   136 CAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPNMGLGR-------------SE 187
            ..|:.||::|:...:.|..::...|...::.:|....|:...||.:|.|.             ..
  Fly   123 AVMAAERWMALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYIDESNPDQLKCIRY 187

Mouse   188 RQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALL-----------RMHRQ 241
            |..||.|       |.|    ::.::..|.:.|.:..|.||:.|...||           .||..
  Fly   188 RDAPGVW-------NKT----YAVLFMVFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYD 241

Mouse   242 FMRR-----------TSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIA--- 292
            .:.|           :|.||..:....:....:    .|....||.|    :|...|....|
  Fly   242 LVSRDKNSAISIDPESSSGTTLYQTQLSTGSGN----SHRSVQPARQ----YRHSVSVTMAATDS 298

Mouse   293 -GAEIQMVILLIATSLVVLICSIPLVVRVFI----NQLYQPN---VVKDISRNPDLQAIRIASVN 349
             ..||:...|:...|:..:||.:|.::.:.:    |::...|   ::.|:     |.|:...|
  Fly   299 SPVEIKFAKLMAFLSISFVICWMPQMIAIPLAIAPNRVPASNKFFIIADV-----LTALHFTS-- 356

Mouse   350 PILDPWIYILLRKTVLSKAIEKIKCLFC--------RIGGSGRDSSAQHCSESRRT 397
               ||::|:|.|    ||:| ....|.|        |.||..|..|.|  |..|.|
  Fly   357 ---DPYVYVLSR----SKSI-NWSLLGCIKRWRSGWRPGGLRRSQSDQ--SRMRTT 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptger4	NP_032991.1	TM helix 6	293..323	CDD:320270	7/33 (21%)
		TM helix 7	336..361	CDD:320270	7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	383..403		6/15 (40%)
		7tmA_PGE2_EP4	43..369	CDD:320270	86/382 (23%)
		TM helix 1	44..70	CDD:320270	7/25 (28%)
		TM helix 2	79..105	CDD:320270	11/36 (31%)
		TM helix 3	117..147	CDD:320270	10/29 (34%)
		TM helix 4	159..181	CDD:320270	5/21 (24%)
		TM helix 5	205..234	CDD:320270	6/28 (21%)
CG7497	NP_648999.2	7tm_GPCRs	34..365	CDD:475119	83/369 (22%)
		TM helix 1	34..55	CDD:410628	7/22 (32%)
		TM helix 2	68..87	CDD:410628	4/18 (22%)
		TM helix 3	99..127	CDD:410628	8/35 (23%)
		TM helix 4	150..166	CDD:410628	2/15 (13%)
		TM helix 5	195..218	CDD:410628	6/26 (23%)
		TM helix 6	306..328	CDD:410628	5/21 (24%)
		TM helix 7	340..365	CDD:410628	9/34 (26%)