DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptger1 and CG7497

DIOPT Version :9

Sequence 1:	XP_006530834.1	Gene:	Ptger1 / 19216	MGIID:	97793	Length:	439	Species:	Mus musculus
Sequence 2:	NP_001287100.1	Gene:	CG7497 / 39966	FlyBaseID:	FBgn0036742	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	441	Identity:	95/441 - (21%)
Similarity:	153/441 - (34%)	Gaps:	118/441 - (26%)

- Green bases have known domain annotations that are detailed below.

Mouse    57 PNTSVVLPTGDNGTSPALP-------------IFSMTLGAVSNVLALALLAQVAGRMRRRRSAAT 108
            |...:::|  .|.|:.|.|             :..|.||...|.|||.:||:   :...:.|..|
  Fly     6 PVLDLLMP--HNSTTVAPPKALYANRNRLIIGVIIMVLGVFGNSLALFILAR---KKLNKNSKYT 65

Mouse   109 FLL--------------FVASLLAIDLAGHVIP--------GALVLRLYTAGRAPAGGACHFLGG 151
            .:|              ...:||.:.|:..|:.        |.:|.|
  Fly    66 LMLRCLATNNLVALLGMLTTTLLKMYLSKEVLQSFIRVDCVGLVVWR------------------ 112

Mouse   152 CMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALAVLAAMALAVALLPLVHVGRYE 216
               ||||....:...||.||.:.:.:|.|:...::....|.::..:..:|:.:..||.|..|.|.
  Fly   113 ---FFGLSSGCIAAVMAAERWMALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYI 174

Mouse   217 ----------LQY---PGTWCFISLGPRGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRA 268
                      ::|   ||.|            ....|.||...|....:..:.||......||..
  Fly   175 DESNPDQLKCIRYRDAPGVW------------NKTYAVLFMVFGTLLCIVIVACNLFVAHTLLCV 227

Mouse   269 RWRRRRSRR-FRKTAGPDDRRRWGSRGPRLASASSASSITSATATLRSSRGGGSARRV-HAHDVE 331
            ..|.|.::| ........|:....|..|..:|.::......:|.:..|.|....||:. |:..|.
  Fly   228 IGRSRTAKRHMHYDLVSRDKNSAISIDPESSSGTTLYQTQLSTGSGNSHRSVQPARQYRHSVSVT 292

Mouse   332 MV-----------GQLVGIMVVS-CICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILD 384
            |.           .:|:..:.:| .|||.|.::.:.|||......:..:...:|..|.:.:...|
  Fly   293 MAATDSSPVEIKFAKLMAFLSISFVICWMPQMIAIPLAIAPNRVPASNKFFIIADVLTALHFTSD 357

Mouse   385 PWVYILLRQAMLRQLLRLLPLRVSAKGGPTELGLTK---SAWEASSLRSSR 432
            |:||:|.|...:...|               ||..|   |.|....||.|:
  Fly   358 PYVYVLSRSKSINWSL---------------LGCIKRWRSGWRPGGLRRSQ 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptger1	XP_006530834.1	7tm_GPCRs	69..394	CDD:391938	83/386 (22%)
		TM helix 1	70..96	CDD:341315	12/38 (32%)
		TM helix 2	109..135	CDD:341315	8/47 (17%)
		TM helix 3	146..176	CDD:341315	8/29 (28%)
		TM helix 4	188..210	CDD:341315	4/21 (19%)
		TM helix 5	235..264	CDD:341315	6/28 (21%)
		TM helix 6	327..357	CDD:341315	8/41 (20%)
		TM helix 7	367..392	CDD:341315	7/24 (29%)
CG7497	NP_001287100.1	7tm_4	36..>221	CDD:304433	46/220 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835068
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8162
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11866
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.940