Sequence 1: | NP_032986.1 | Gene: | Pten / 19211 | MGIID: | 109583 | Length: | 403 | Species: | Mus musculus |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001162933.1 | Gene: | Pten / 43991 | FlyBaseID: | FBgn0026379 | Length: | 514 | Species: | Drosophila melanogaster |
Alignment Length: | 405 | Identity: | 168/405 - (41%) |
---|---|---|---|
Similarity: | 232/405 - (57%) | Gaps: | 61/405 - (15%) |
- Green bases have known domain annotations that are detailed below.
Mouse 1 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPA-ERLEGVYRNNIDDVVRFLDSKHKNH 64
Mouse 65 YKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKG 129
Mouse 130 RTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALL 194
Mouse 195 FHKMMFETIPMFSGGTC--NPQFVVCQLKVKIYSS---NSGPTRRE------DKFMYFEFPQPLP 248
Mouse 249 VCGDIKVEFFHKQNKMLKKDKMF-HFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADND 312
Mouse 313 KEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASS-STSVTPDVSDNEPD- 375
Mouse 376 ---HYRYSDTTDSDP 387 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Pten | NP_032986.1 | PTP_PTEN | 24..181 | CDD:350359 | 101/157 (64%) |
PTEN_C2 | 188..349 | CDD:402161 | 47/172 (27%) | ||
Required for interaction with NOP53. /evidence=ECO:0000250|UniProtKB:P60484 | 338..348 | 3/9 (33%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 352..403 | 9/41 (22%) | |||
PDZ domain-binding. /evidence=ECO:0000250 | 401..403 | ||||
Pten | NP_001162933.1 | PTPc | 58..167 | CDD:304379 | 66/108 (61%) |
PTEN_C2 | 196..335 | CDD:287393 | 39/150 (26%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C167849519 | |
Domainoid | 1 | 1.000 | 118 | 1.000 | Domainoid score | I5866 |
eggNOG | 1 | 0.900 | - | - | E2759_KOG2283 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 1 | 1.000 | - | - | H265 | |
Inparanoid | 1 | 1.050 | 284 | 1.000 | Inparanoid score | I2848 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 1 | 1.010 | - | - | QHG52467 | |
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0001369 | |
OrthoInspector | 1 | 1.000 | - | - | oto93632 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_100936 | |
Panther | 1 | 1.100 | - | - | LDO | PTHR12305 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1027 |
SonicParanoid | 1 | 1.000 | - | - | X965 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 1 | 0.960 | - | - | ||
15 | 14.790 |