DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Psmc2 and Rpt6

DIOPT Version :9

Sequence 1:	NP_001355590.1	Gene:	Psmc2 / 19181	MGIID:	109555	Length:	433	Species:	Mus musculus
Sequence 2:	NP_608447.1	Gene:	Rpt6 / 33105	FlyBaseID:	FBgn0020369	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	388	Identity:	190/388 - (48%)
Similarity:	254/388 - (65%)	Gaps:	23/388 - (5%)

- Green bases have known domain annotations that are detailed below.

Mouse    38 QSTYSRQIKQVE-------DDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQV 95
            :|.|.::|::::       .::::|..:.|||..           .:..|..:.|.|| ||...|
  Fly    20 RSYYIQKIEELQLVVAEKHQNLRRLQAQRNELNA-----------KVRMLREELQLLQ-EQGSYV 72

Mouse    96 ARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPT 160
            ....|    ..:..|.::.|....||||||...:...|:....||.:....|.:|..||.|:||.
  Fly    73 GEVVK----PMDKKKVLVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPL 133

Mouse   161 VTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLC 225
            |::|.||:.||.||..|||..:||::::||:|.|:.|||.|..|||..||||||:|||||||||.
  Fly   134 VSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLL 198

Mouse   226 ARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAG 290
            |||||:.|:..||||.|||||||::|||:|||||||.|||.....:||.||||:||.:|.:.|:|
  Fly   199 ARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRIESGSG 263

Mouse   291 GDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIF 355
            ||:|||||||||:||||||:...||||:|||||.|.|||||:||||:||||||..|:.|.|..|.
  Fly   264 GDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEARLDIL 328

Mouse   356 KIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIK 418
            |||:|.|::.|.|....:|.|.|.::|||::.|||||||:|:|.||...|::||..||.||::
  Fly   329 KIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQ 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Psmc2	NP_001355590.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
Psmc2	NP_001355590.1	RPT1	23..430	CDD:224143	190/388 (49%)
Rpt6	NP_608447.1	RPT1	17..403	CDD:224143	190/388 (49%)
		SlyX	<27..>69	CDD:294687	10/53 (19%)
		AAA_16	152..>205	CDD:289934	34/52 (65%)
		AAA	185..317	CDD:278434	94/131 (72%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820