DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment old-1 and btl

DIOPT Version :9

Sequence 1:NP_496130.2 Gene:old-1 / 191737 WormBaseID:WBGene00003862 Length:502 Species:Caenorhabditis elegans
Sequence 2:NP_001014583.1 Gene:btl / 39564 FlyBaseID:FBgn0285896 Length:1052 Species:Drosophila melanogaster


Alignment Length:328 Identity:117/328 - (35%)
Similarity:182/328 - (55%) Gaps:35/328 - (10%)


- Green bases have known domain annotations that are detailed below.


 Worm   167 EINEEDLDISKGRPLGSGEFGII----RKGFLRSKNSKNEEKESRLEVAVKLPLNEYNQIQQELI 227
            ||..:.|  |.|..||.|.||.:    .:|..||      .:.:...||||:...|:.......:
  Fly   706 EIPRQQL--SLGSILGEGAFGRVVMAEAEGLPRS------PQLAETIVAVKMVKEEHTDTDMASL 762

 Worm   228 YDELKVMCAVGKHPNILALVGGITFGERKMIVSEFVENGDLLSFLRDNR----------IYFTND 282
            ..|::||..:|||.||:.|:|..:.|....::.|:..:|:|..||:.||          ..:.:|
  Fly   763 VREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDD 827

 Worm   283 QWTLETEQDSLSLVDLLSFAFQIAKGMEYLIHVPCVHRDLALRNVLIKKNRIIRIADFGLARRHK 347
            :..:.|:.  |...:|..||||||:|||||....|:|||||.||||:....:::||||||||..:
  Fly   828 KPLISTQH--LGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQ 890

 Worm   348 NKDYYKTQSVDTPLPIHWMAPESIDKLLFTQKSDVWSYGVCLYELFSLGKSPYENVIKYDQRDFY 412
            :.:||: ::.:..|||.||||||:.:..:..:||||||||.|:|:.:.|..||.:::..::    
  Fly   891 DTEYYR-KNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEE---- 950

 Worm   413 WKYVLSYLNEGKRLAQPAHADAEIYNVMKLCWDLDMNSRTTFLDCIEFFEKELKTTS---NEYFL 474
               :.|||..|:|:.:||.....||.||:.||..:..:|.||.:.:|.|:..|:..|   |:.:|
  Fly   951 ---LYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYL 1012

 Worm   475 DLT 477
            ||:
  Fly  1013 DLS 1015

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
old-1NP_496130.2 TyrKc 175..461 CDD:197581 107/299 (36%)
PTKc 179..462 CDD:270623 105/296 (35%)
btlNP_001014583.1 IG_like 149..232 CDD:214653
IGc2 157..215 CDD:197706
IG 247..336 CDD:214652
Ig 258..340 CDD:143165
I-set 394..479 CDD:254352
IGc2 408..469 CDD:197706
IG_like 492..583 CDD:214653
Ig 507..583 CDD:299845
PKc_like 700..1000 CDD:304357 111/311 (36%)
TyrKc 712..996 CDD:197581 108/301 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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