Protein Alignment gcy-27 and Gyc76C

DIOPT Version :10

• Sequence 1: NP_001255957.2
• Gene: gcy-27 / 191654
• WormBaseID: WBGene00001550
• Length: 616
• Species: Caenorhabditis elegans
• Sequence 2: NP_001163473.1
• Gene: Gyc76C / 8674026
• FlyBaseID: FBgn0266136
• Length: 1525
• Species: Drosophila melanogaster
• Alignment Length: 602
• Identity: 188/602 - (31%)
• Similarity: 313/602 - (51%)
• Gaps: 71/602 - (11%)

 Worm    29 RKYK-------MTWKVPKESLK-----IIVNKNADARMQRELENRTAKDEANALTSRRRVFGSYA 81
            ||:|       :.||:....:|     .||:..:...:. ..::..::.....:||..|:.|  |
  Fly   515 RKWKIELEIEGLLWKIDPNEIKGYSGNEIVSSPSKVSLM-SAQSYGSRWTNQFVTSTGRLRG--A 576

 Worm    82 LIGTQRAEFIQFRQIKHIDITNASLDFLYNLKQLKHDNLANFYGIQLNDDLNTMTILHALVERGT 146
            ::..:..:|.:.|     ||:...:..:..|::|:|||:.:|.|..:  :...:.::.....:|:
  Fly   577 VVRIKELKFPRKR-----DISREIMKEMRLLRELRHDNINSFIGASV--EPTRILLVTDYCAKGS 634

 Worm   147 LEEFCLDRDFGMDETFKSAFMRDILKGLQYLHLSPVAYHGHLHAATCLIDINWVLKIALYGVTNF 211
            |.:...:.|..:|:.|.::.:.|::||:.|:|.|.:.|||:|.::.|::...|:|::..:|:...
  Fly   635 LYDIIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHEL 699

 Worm   212 -VCDNFDAENITMPDRSDYTISYAQYVCFPPEHIREYDATGKLPTRFVRGSKQGDIYCVGMIFYM 275
             .|    |||.::.:..    .|...:...||.:|.:          :.||::||:|...:|.|.
  Fly   700 RQC----AENESIGEHQ----HYRNQLWRAPELLRNH----------IHGSQKGDVYAFAIIMYE 746

 Worm   276 MIEREDPYRLIHSVERPGSGLMMEILDH-------NLMPF------ISNNETQEDTLLDKCKECW 327
            :..|:.|:..|:...:       ||:|:       ...||      |...|:..|.:|...::||
  Fly   747 IFSRKGPFGQINFEPK-------EIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCW 804

 Worm   328 NRDPEKRPTIENLRNAIAICYADSKGNLIDQMIRMNEKYADELETLVAARSADLALAQMQTMRLL 392
            ..|||:||....:||.:.........|::|||:.|.||||:.||.:|..|:..|...:|:|..||
  Fly   805 AEDPEERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLL 869

 Worm   393 NEMLPASIAKDLKNGVIAPARSYASATVMFVQICDFIVILKRRPPKEVIGFLNDIFDQFDTVIKR 457
            :.|||.|:|:.|..|......||...|:.|..|..|..:.....|.:|:.||||::..||.:|:.
  Fly   870 HRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRG 934

 Worm   458 HDAYKVETTGETYMVASGVPNENEGRHVFEVAEMSLEIRAISLSYTLENDKNYKLRVRIGFHAGP 522
            :|.|||||.|:.|||.||:|.:|..||..|:|.|:||:......:.:.:..|..|::|||.|.||
  Fly   935 YDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGP 999

 Worm   523 IAAGVIGIKNPRYCLFGDTVNFASRMQSNCPPLQIQTSEITARMLLATHE----YKLVKRGIVHV 583
            :.|||:|:..|||||||||||.||||:||...|:|   .|:.:..||..:    |...|||:|::
  Fly  1000 VVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKI---HISNKCKLALDKLGGGYITEKRGLVNM 1061

 Worm   584 KGKGEVNCYWL---NEH 597
            ||||:|..:||   ||:
  Fly  1062 KGKGDVVTWWLTGANEN 1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gcy-27	NP_001255957.2	Protein Kinases, catalytic domain	75..338	CDD:473864	67/276 (24%)
		CYCc	383..573	CDD:214485	81/193 (42%)
Gyc76C	NP_001163473.1	PBP1_SAP_GC-like	26..445	CDD:380593
		PK_GC-A_B	543..827	CDD:270944	73/318 (23%)
		HNOBA	<833..881	CDD:462234	22/47 (47%)
		CYCc	860..1052	CDD:214485	81/194 (42%)