Protein Alignment PHC1 and pqn-26

DIOPT Version :9

• Sequence 1: XP_011518905.1
• Gene: PHC1 / 1911
• HGNCID: 3182
• Length: 1021
• Species: Homo sapiens
• Sequence 2: NP_492375.3
• Gene: pqn-26 / 183974
• WormBaseID: WBGene00004115
• Length: 664
• Species: Caenorhabditis elegans
• Alignment Length: 796
• Identity: 186/796 - (23%)
• Similarity: 258/796 - (32%)
• Gaps: 251/796 - (31%)

Human    97 ASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTS-PPLN 160
            ||..|:...|:..|||....|..     ...:|....|.| |.|::.|.||.    .|.| .|..
 Worm    19 ASTLANIYGTAEIQQQQYQQQQQ-----PQYSQSYGESPS-SFPTSFTYTQP----ETQSYQPSQ 73

Human   161 QSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNL 225
            ||.|..      .||...:......:...||....||.|....     :|.|....|.....|..
 Worm    74 QSSASS------SNLQFHSYNSQPGIQYGSQDSFYPNQAALTA-----AATSFATSAAQQYAQTY 127

Human   226 AVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGN 290
            :.:.||...|.|..                           :.||:....:|.|::.|.  ..|.
 Worm   128 SQQQQQQQVQAPAQ---------------------------IDQANLAKYSQYLDILQK--AYGI 163

Human   291 SIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKK 355
            .:||.|.                               :||..||   |.:.|.||..:...|.:
 Worm   164 QLPGEMS-------------------------------MQPNTAA---TNAGGYQTSQQQQVANQ 194

Human   356 A-EADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQ-QKQVVIQQQIAI 418
            . :..|..||           |.|:||...       .|.::.|.|.|::.| |.::..|||:|.
 Worm   195 VPQTYGQSQQ-----------PPPTQTYSG-------YPQNVAQPQPQVNTQSQAEITYQQQLAA 241

Human   419 HHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPT----QQVPPS 479
            :.|||.|..|.|.|.....|...||:|||||||..|||..|..:.|.|..|....    ||...:
 Worm   242 YQQQQQQIAQQQQLQQQQQLAAEQQKQQQQQQQIAQQQQLAEQIAAQQAQQREAARLAQQQAQQA 306

Human   480 QSQQQAQTLVVQPMLQSSPL--------SLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQ 536
            |..||.|..:.|..||....        .:.|:...:|..|:|.:  :|  :||         .|
 Worm   307 QQAQQLQQQIRQQQLQQQQQQQQQNQYGGMQPNPYVQPQAPVQQQ--IA--QPP---------PQ 358

Human   537 QPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ- 600
            ||.|..|:..:...|....||                                 |:.|||..:|
 Worm   359 QPAPQQPMNFLPAPQAPIIQA---------------------------------PAPQAPAPMQP 390

Human   601 --------ECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVK 657
                    ..|||.......|.: |..:...|   .|.|.|...|..   ..|.:|  ..:.:..
 Worm   391 QQPPKQYVTQPPTYKNNYQTAAL-GQVNTYSG---QSKPQVYTYPGP---SQVQIP--THSTSYG 446

Human   658 RKADS---EEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNAN---------- 709
            ...||   ||....|.:...::|.:  ||...|.:            |||.|...
 Worm   447 NHEDSVIEEEPHGSVISQQQVVPPR--PVQPVPPM------------SVATVTRGPPPPTRPASV 497

Human   710 -TPSSELVALT---PAPSVPPPTLAMV----SRQMGDSKPPQA---IVKP---QILTHIIEGF-- 758
             .|||.:|..:   |:|:..|||.|.:    ..:...|:|..|   :|.|   |.||..|...
 Worm   498 IAPSSSVVPKSQPRPSPTTRPPTRATIRPTPQNKAVTSRPAPATSSVVTPSPSQSLTQQIRKLPA 562

Human   759 VIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGGPL------GVDSPSA------ELDKK 811
            |:...::          .||.|..:|     |..:..|.||      ..|.|:|      :|...
 Worm   563 VLYIDSK----------NESTKKTET-----LLRDTYGLPLVTFYVDKTDKPAAIQRQLQQLTAH 612

Human   812 ANLLKCEYCGKYAPAE 827
            ..|.....||.:..:|
 Worm   613 KGLPYLFICGTFIGSE 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHC1	XP_011518905.1	zf-FCS	809..844	CDD:283998	4/19 (21%)
		PHC2_SAM_assoc	845..951	CDD:293222
		SAM_Ph1,2,3	952..1020	CDD:188976
		SAM	954..1021	CDD:197735
pqn-26	NP_492375.3	Thioredoxin_like	574..643	CDD:381987	14/60 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000