DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Prkx and for

DIOPT Version :9

Sequence 1:NP_058675.1 Gene:Prkx / 19108 MGIID:1309999 Length:355 Species:Mus musculus
Sequence 2:NP_477487.1 Gene:for / 44817 FlyBaseID:FBgn0000721 Length:1088 Species:Drosophila melanogaster


Alignment Length:341 Identity:144/341 - (42%)
Similarity:207/341 - (60%) Gaps:10/341 - (2%)


- Green bases have known domain annotations that are detailed below.


Mouse    17 DPVKTKVSAPAADPKPRTSSQKAGHSLQDWDTIATVGTGTFGRVNLVKEK--TGRQYCALKIMSI 79
            |.:|.:.....|..:.:.:.:....:|.|...|||:|.|.||||.||:..  :.|.: |||.|..
  Fly   748 DEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSF-ALKQMKK 811

Mouse    80 PDVIRLKQEQHVQNEKAVLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSV 144
            ..::..:|:||:.:||.::.|.|..|::||..|..|.::||||||...||||:|.||::|.|...
  Fly   812 SQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDS 876

Mouse   145 ASVFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVD--RTWTLCGTPEY 207
            .:.||...:|.|.:||||:.|:||||||||:||:..|::||.||||||||..  :|||.||||||
  Fly   877 TTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEY 941

Mouse   208 LAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKIL--ACKIDFPRQLDFTSKD 270
            :|||||.::||..:.|:|:||:|:||:|:|.|||...:|...|..||  ...|:|||.:...:.:
  Fly   942 VAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASN 1006

Mouse   271 LIKKLLVVDRTRRLGNMKNGAEDIKRHRWFRGVEWESVPQRKLKPPIVPKLSGDGDISNFETYPE 335
            |||||...:...|||..:.|..:|::|:||.|..|..:....|:|||.|.:....|.:||:.||.
  Fly  1007 LIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPP 1071

Mouse   336 SELDKTP-SVS--DKD 348
            ......| .|:  |||
  Fly  1072 DPEGPPPDDVTGWDKD 1087

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PrkxNP_058675.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..42 3/24 (13%)
PTZ00263 31..355 CDD:140289 141/327 (43%)
STKc_PRKX_like 44..335 CDD:270763 134/296 (45%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 316..355 13/36 (36%)
forNP_477487.1 DD_cGKI-alpha 385..432 CDD:213374
Crp 518..>627 CDD:223736
CAP_ED 520..629 CDD:237999
Crp 632..>753 CDD:223736 2/4 (50%)
CAP_ED 638..754 CDD:237999 2/5 (40%)
S_TKc 778..1036 CDD:214567 120/258 (47%)
STKc_cGK 783..1043 CDD:270724 121/260 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0616
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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