Protein Alignment AHCY and AhcyL2

DIOPT Version :9

• Sequence 1: NP_001309015.1
• Gene: AHCY / 191
• HGNCID: 343
• Length: 434
• Species: Homo sapiens
• Sequence 2: NP_996221.1
• Gene: AhcyL2 / 42043
• FlyBaseID: FBgn0015011
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 424
• Identity: 217/424 - (51%)
• Similarity: 301/424 - (70%)
• Gaps: 1/424 - (0%)

Human    10 CEADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGA 74
            |...|..:|:||:.::|||:||||:|.:|:|....||||||.|.||.|:..::||||||||.|||
  Fly    69 CVKSISKSAFGRREIEIAESEMPGIMTLRKRAKDEKPLKGANIVGCTHVNAQSAVLIETLVQLGA 133

Human    75 EVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTN 139
            .|:|::|||:|||:..|||:|:||||::||:|||:||:.||:::.:|......|:|||||||.|:
  Fly   134 TVRWAACNIYSTQNAVAAALAEAGIPIFAWRGETEEEFWWCLDRAIYSDGWQPNLILDDGGDATH 198

Human   140 LIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDG 204
            |:..|||.....||||.||:.||||.||.:...|.|.||||||||||||:|||..|.||:|::|.
  Fly   199 LMLKKYPDYFKAIRGIVEESVTGVHRLYMLSKGGKLTVPAINVNDSVTKNKFDTFYTCRDSILDS 263

Human   205 IKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQ 269
            :||.||:|..||..|:.|||||||||||:|:|.|..|.:||:|||.||||||:|:.|..::|..:
  Fly   264 LKRTTDIMFGGKQVVICGYGDVGKGCAQSLKGQGCIVYVTEVDPICALQAAMDGFRVVRLNEVIR 328

Human   270 EGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKN 334
            ..::.||.||..::|...|..:||:..|:||:||...||||..|:...:....::.|||..|..:
  Fly   329 TVDVVVTATGNKNVITRDHMNRMKNGCILCNMGHSCSEIDVNGLHTPELTWERVRSQVDHIRWPD 393

Human   335 GRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEA 399
            ||.||||||||||||.|:. ..|||:|.:.:.|.:|.|||::.|.:|...|:.||||:||.||..
  Fly   394 GRMIILLAEGRLVNLSCST-ISSFVVSVASSTQALALIELFSAPGRYKSDVYLLPKKMDEYVASL 457

Human   400 HLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYR 433
            ||...:..||:||::|::::|::..||||.::||
  Fly   458 HLATFDAHLTELTDEQSKFMGLNKAGPFKANYYR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AHCY	NP_001309015.1	AdoHcyase	10..433	CDD:283003	215/422 (51%)
		PRK05476	12..428	CDD:235488	212/415 (51%)
AhcyL2	NP_996221.1	PRK05476	63..486	CDD:235488	213/417 (51%)
		AdoHcyase	67..491	CDD:283003	215/422 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0499
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S93
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D371693at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.770