Protein Alignment AHCY and AhcyL1

DIOPT Version :9

• Sequence 1: NP_001309015.1
• Gene: AHCY / 191
• HGNCID: 343
• Length: 434
• Species: Homo sapiens
• Sequence 2: NP_647746.1
• Gene: AhcyL1 / 38342
• FlyBaseID: FBgn0035371
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 427
• Identity: 220/427 - (51%)
• Similarity: 307/427 - (71%)
• Gaps: 3/427 - (0%)

Human    10 CEADIGLA-AWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLG 73
            |..:||.. |:||:.::|||.||||::.:::|.:..||||.|:|.||.|:..:|||||||||.||
  Fly    96 CVRNIGAQHAFGRREIEIAEQEMPGIIALKKRAAEDKPLKDAKIVGCTHINAQTAVLIETLVELG 160

Human    74 AEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLT 138
            |.|:|::|||:|||:..|||:|::|||::||:|||:|::.|||::.:..::...|||||||||.|
  Fly   161 ASVRWAACNIYSTQNEVAAALAESGIPIFAWRGETEEDFWWCIDRCVNAENWQPNMILDDGGDAT 225

Human   139 NLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLID 203
            :|:..|||.:...::||.||:.||||.||::...|.|.|||:||||||||:||||||.|:||::|
  Fly   226 HLMLKKYPTMFKLVKGIVEESVTGVHRLYQLSKAGKLTVPAMNVNDSVTKTKFDNLYSCKESILD 290

Human   204 GIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEAC 268
            .:||:||||..||..||.|||||||||||||:|.|..|.|||||||.||||:|:|:.|..::|..
  Fly   291 SLKRSTDVMFGGKQVVVCGYGDVGKGCAQALKGQGCIVYITEIDPICALQASMDGFRVVKLNEVI 355

Human   269 QEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLK 333
            :..:|.||.||..::::..|.::||...||||:||.:.||||..|....:....::.|||.....
  Fly   356 RNVDIVVTATGNKNVVVREHMDKMKSGCIVCNMGHSNTEIDVNGLRTPDLTWEKVRSQVDHIIWP 420

Human   334 NGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELW-THPDKYPVGVHFLPKKLDEAVA 397
            .|:.||||||||||||.|: ..|||.:|.:...|.:|.|||: ..|.:|...|:.||||:||.||
  Fly   421 EGKYIILLAEGRLVNLSCS-SIPSFAVSITSATQALALIELFNAPPGRYKSDVYLLPKKMDEYVA 484

Human   398 EAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 434
            ..||...:..||:|:::||:|:|::..|||||::|||
  Fly   485 SLHLPTFDAHLTELSDEQAKYMGLNKAGPFKPNYYRY 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AHCY	NP_001309015.1	AdoHcyase	10..433	CDD:283003	217/424 (51%)
		PRK05476	12..428	CDD:235488	213/417 (51%)
AhcyL1	NP_647746.1	AdoHcyase	94..520	CDD:336064	217/424 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0499
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D371693at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820