back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prkg1 and Pka-C1

DIOPT Version :10

Sequence 1:	NP_035290.1	Gene:	Prkg1 / 19091	MGIID:	108174	Length:	686	Species:	Mus musculus
Sequence 2:	NP_476977.1	Gene:	Pka-C1 / 34284	FlyBaseID:	FBgn0000273	Length:	353	Species:	Drosophila melanogaster

Alignment Length:	342	Identity:	147/342 - (42%)
Similarity:	208/342 - (60%)	Gaps:	15/342 - (4%)

- Green bases have known domain annotations that are detailed below.

Mouse   340 IGGLDDVSNKAYEDAEA------KAKYEAEAAFFAN----LKLSDFNIIDTLGVGGFGRVELVQL 394
            :|.....|||..:.||.      :||.|.|..:..|    ..|.||..|.|||.|.||||.:||.
  Fly     1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQH 65

Mouse   395 KSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGG 459
            |..:. .:|||||.|:.:|..:|.||..:||:|:|.....|:|.|...|||:..|||::|...||
  Fly    66 KPTKD-YYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGG 129

Mouse   460 ELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI 524
            |:::.||..|.|.:..:|||.|.:|.||.|||...:||||||||||::|.:||.|:.||||||::
  Fly   130 EMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRV 194

Mouse   525 GFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGI 589
              ..:|||.||||||:||||||:||::.:.|:|:||:|:||:..|.|||....|::.|..|:.|
  Fly   195 --KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSG- 256

Mouse   590 DMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPS 654
             .:.||.....:..:|::.|.:.:.::|.||||.||.||:..|||...:|..:.:..:..|.||.
  Fly   257 -KVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPR 320

Mouse   655 VASPTDTSNFDSFPEDS 671
            ...|.||||||.:.|::
  Fly   321 CKGPGDTSNFDDYEEEA 337

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.