DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment EDNRA and Ednra

DIOPT Version :9

Sequence 1:NP_001948.1 Gene:EDNRA / 1909 HGNCID:3179 Length:427 Species:Homo sapiens
Sequence 2:NP_034462.1 Gene:Ednra / 13617 MGIID:105923 Length:427 Species:Mus musculus


Alignment Length:427 Identity:394/427 - (92%)
Similarity:411/427 - (96%) Gaps:0/427 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSM 65
            |...||.|.|||.:||.|::|||||||.|||:|::|||.|.|||::||.|||:|.||.|||||||
Mouse     1 MSIFCLAAYFWLTMVGGVMADNPERYSANLSSHMEDFTPFPGTEINFLGTTHRPPNLALPSNGSM 65

Human    66 HNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYV 130
            |.|||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 HGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYV 130

Human   131 VIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQG 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 VIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQG 195

Human   196 IGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLF 260
            |||||:||||||||||||||||||||||||||||||:||.|:|||||||||||||||||||||||
Mouse   196 IGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGELHRTCMLNATSKFMEFYQDVKDWWLF 260

Human   261 GFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLS 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 GFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLS 325

Human   326 RILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQ 390
            ||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||:|
Mouse   326 RILKKTVYDEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCHQ 390

Human   391 SKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN 427
            |||||||||||||||||||.:||||||:|||||||||
Mouse   391 SKSLMTSVPMNGTSIQWKNQEQNNHNTERSSHKDSMN 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EDNRANP_001948.1 7tmA_ET-AR 81..380 CDD:320641 293/298 (98%)
TM helix 1 82..108 CDD:320641 25/25 (100%)
TM helix 2 115..141 CDD:320641 25/25 (100%)
TM helix 3 158..188 CDD:320641 29/29 (100%)
TM helix 4 200..220 CDD:320641 18/19 (95%)
TM helix 5 252..277 CDD:320641 24/24 (100%)
TM helix 6 299..329 CDD:320641 29/29 (100%)
TM helix 7 348..373 CDD:320641 24/24 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 406..427 17/20 (85%)
EdnraNP_034462.1 7tm_1 97..367 CDD:278431 264/269 (98%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 408..427 15/18 (83%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C83966088
Domainoid 1 1.000 548 1.000 Domainoid score I6245
eggNOG 00.000 Not matched by this tool.
HGNC 1 1.500 - -
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H1478
Inparanoid 1 1.050 824 1.000 Inparanoid score I7652
Isobase 00.000 Not matched by this tool.
NCBI 1 1.000 - -
OMA 1 1.010 - - QHG43925
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0010775
OrthoInspector 1 1.000 - - oto112078
orthoMCL 1 0.900 - - OOG6_117506
Panther 1 1.100 - - LDO PTHR46099
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X6586
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
1414.400

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