Protein Alignment Pou5f1 and pdm2

DIOPT Version :10

• Sequence 1: NP_038661.2
• Gene: Pou5f1 / 18999
• MGIID: 101893
• Length: 352
• Species: Mus musculus
• Sequence 2: NP_723763.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 102/244 - (41%)
• Similarity: 143/244 - (58%)
• Gaps: 43/244 - (17%)

Mouse    92 GQAGARVESNSEGTSSEP----CADRPN-----AVKLEKVEPTPEESQDMKALQKELEQFAKLLK 147
            |.:.|.:..|:.....:|    ...:|.     |..:.|:|.:|||:.|:    :|||||||..|
  Fly   637 GMSSAVMTPNTPSMQQQPQLQQSTPKPTSGLTVASAMAKLEQSPEETTDL----EELEQFAKTFK 697

Mouse   148 QKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSLKNMCKLRPLLEKWVEEADNNENLQE 212
            |:||.||:||.||||.:|.|:|..||||||.|||||.||.||||||:|||:||:|:||:.
  Fly   698 QRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADST----- 757

Mouse   213 ICKS------------------ETLVQARKRKRTSIENRVRWSLETMFLKCPKPSLQQITHIANQ 259
            :.||                  |:::..|::||||||..||.:||..||...||:.::|:.::.:
  Fly   758 VAKSGGGVFNINTMTSTLSSTPESILGRRRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSER 822

Mouse   260 LGLEKDVVRVWFCNRRQKGKR--SSIEYSQREEYEATGTPFPGGAVSFP 306
            |.::|:|:||||||||||.||  .|::..     ..||||....|..:|
  Fly   823 LNMDKEVIRVWFCNRRQKEKRINPSLDLD-----SPTGTPLSSHAFGYP 866

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pou5f1	NP_038661.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		9aaTAD. /evidence=ECO:0000250|UniProtKB:Q01860	4..12
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..115		4/26 (15%)
		POU	131..205	CDD:197673	48/73 (66%)
		DNA-binding. /evidence=ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P	173..179		5/5 (100%)
		DNA-binding. /evidence=ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P	186..189		1/2 (50%)
		Homeodomain	224..280	CDD:459649	28/55 (51%)
pdm2	NP_723763.1	PHA03247	<375..675	CDD:223021	6/37 (16%)
		POU	691..755	CDD:197673	44/63 (70%)
		Homeodomain	787..843	CDD:459649	28/55 (51%)