DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pou3f4 and Antp

DIOPT Version :9

Sequence 1:	NP_032927.1	Gene:	Pou3f4 / 18994	MGIID:	101894	Length:	361	Species:	Mus musculus
Sequence 2:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	399	Identity:	68/399 - (17%)
Similarity:	111/399 - (27%)	Gaps:	185/399 - (46%)

- Green bases have known domain annotations that are detailed below.

Mouse    90 LGAIIHH-----------RSPHVAHHSPHTNHPNAWGASPAP-----------NSSITSSGQPLN 132
            :||.:||           .:..:.|:|.:.||.   |..|.|           |.......|...
  Fly    20 MGADMHHGHYPGNGVTDLDAQQMHHYSQNANHQ---GNMPYPRFPPYDRMPYYNGQGMDQQQQHQ 81

Mouse   133 VYSQPGFTVSGMLEHGGLTPPPAAASTQSLHPVLREPPDHGELGSHHCQDHSDEETPTSDELEQF 197
            |||:|.   |...:.||:.|               :...:|:||... |....::.|:.::.:|.
  Fly    82 VYSRPD---SPSSQVGGVMP---------------QAQTNGQLGVPQ-QQQQQQQQPSQNQQQQQ 127

Mouse   198 AKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLN--KWLEEAD 260
            |:|..|:              |......|..|.|..:.:..|......|||:..:.  ..:.|.
  Fly   128 AQQAPQQ--------------LQQQLPQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEG- 177

Mouse   261 SSTGSPTSIDKIAA------------QGRKRKKRTSIEVSVKGVLETH----------------- 296
               |||..:|:::.            .|..:.:....:|.|..|.|.|
  Fly   178 ---GSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPP 239

Mouse   297 ---------------------------------------------------FLKC-PKPAAQEIS 309
                                                               |.|| .:...::..
  Fly   240 VGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTY 304

Mouse   310 SLADSLQLEKEV------------------------VRVWFCNRRQKEKR--------------- 335
            :...:|:||||.                        :::||.|||.|.|:
  Fly   305 TRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGD 369

Mouse   336 -MTPPGDQQ 343
             :|||...|
  Fly   370 EITPPNSPQ 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pou3f4	NP_032927.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	99..131		9/42 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	144..192		8/47 (17%)
		POU	186..260	CDD:197673	14/75 (19%)
		Homeobox	281..335	CDD:395001	19/146 (13%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	334..361		5/26 (19%)
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	17/148 (11%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	11/52 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3844
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030