DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pou3f4 and nub

DIOPT Version :9

Sequence 1:NP_032927.1 Gene:Pou3f4 / 18994 MGIID:101894 Length:361 Species:Mus musculus
Sequence 2:NP_001097153.1 Gene:nub / 34669 FlyBaseID:FBgn0085424 Length:961 Species:Drosophila melanogaster


Alignment Length:368 Identity:146/368 - (39%)
Similarity:180/368 - (48%) Gaps:85/368 - (23%)


- Green bases have known domain annotations that are detailed below.


Mouse    13 SSSSLVHADSAGMQQGSPFRNPQ----KLLQSDYLQGVPSNGHPLGHHWVTSLSDGGPWSSTLAT 73
            |...|:.:.|.|:.|..|....|    :.|....||.:......|                    
  Fly   625 SYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQLQALSQASQQL-------------------- 669

Mouse    74 SPLDQQDVKPGREDLQLGAIIHHR------------------------SPHVAHHSPHTNHPNAW 114
            ..|.:|..:...|.|||    :|:                        ||...||  |.:|| ..
  Fly   670 QALQKQQQRQVDEPLQL----NHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHH--HHHHP-LQ 727

Mouse   115 GASPAPNSSITSSGQPLNVYSQPGFTVSG-MLEHGGLTPPPAAASTQSLHPVLREPPDHGELGSH 178
            ...|:..:|:..||.     ..|....|| .:..|..||.|...::.:......||         
  Fly   728 ITPPSSAASLKLSGM-----LTPSTPTSGTQMSQGTTTPQPKTVASAAAARAAGEP--------- 778

Mouse   179 HCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFK 243
                 |.|||...:|||||||.||||||||||||.|||||:|.||||.||||||.|||||.||||
  Fly   779 -----SPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK 838

Mouse   244 NMCKLKPLLNKWLEEAD---SSTG---SPTSIDKIAAQ----GRKRKKRTSIEVSVKGVLETHFL 298
            |||||||||.|||::||   .:||   .|.::....:.    ||:||||||||.:::|.||..||
  Fly   839 NMCKLKPLLQKWLDDADRTIQATGGVFDPAALQATVSTPEIIGRRRKKRTSIETTIRGALEKAFL 903

Mouse   299 KCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGD 341
            ...||.::||:.|||.|.:||||||||||||||||||:.|..|
  Fly   904 ANQKPTSEEITQLADRLSMEKEVVRVWFCNRRQKEKRINPSLD 946

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pou3f4NP_032927.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 99..131 10/31 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 144..192 10/47 (21%)
POU 186..260 CDD:197673 59/73 (81%)
Homeobox 281..335 CDD:395001 35/53 (66%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 334..361 4/8 (50%)
nubNP_001097153.1 DUF4472 315..>399 CDD:291409
POU 791..855 CDD:197673 53/63 (84%)
Homeobox 886..939 CDD:278475 34/52 (65%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3802
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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