Protein Alignment zeel-1 and CG12084

DIOPT Version :10

• Sequence 1: NP_490966.2
• Gene: zeel-1 / 189770
• WormBaseID: WBGene00021463
• Length: 917
• Species: Caenorhabditis elegans
• Sequence 2: NP_612112.1
• Gene: CG12084 / 192509
• FlyBaseID: FBgn0043458
• Length: 793
• Species: Drosophila melanogaster
• Alignment Length: 828
• Identity: 157/828 - (18%)
• Similarity: 304/828 - (36%)
• Gaps: 237/828 - (28%)

 Worm   193 LNVNALKKNERKEGFLNHCNTAYRLPHKMTSSLANITAAQIARHINDGRYTRTNILEGMDTKFRD 257
            ||...:..||..:|||.:..   |....:..|        :.|...|...|...|:     ..|:
  Fly    46 LNPGIVLPNEICDGFLENYQ---RFNRPLDDS--------VIRLFEDTHRTSLKIV-----NLRN 94

 Worm   258 TILSKLLLLNPKAYQFIAKTTQVEKSLSIGKRVFELEYYARHKSIITTLTIVLHKKKYWEKIQKL 322
            :.||.:.|.....::..|.:......:|:|.......|....:|:  .|.|..|..:|.|..:|.
  Fly    95 STLSSIGLETLMRHKLFALSLWYCDMISVGSHHLLAHYGDSLRSL--ELGISSHLLQYAEPNEKE 157

 Worm   323 DIRECEAQLTPGWVKQI---GIMLSSLTTLEISNKPLSKEDFSELCDSFPNLVQLDISDTGIR-- 382
            .:   :.|||...::::   |:::.            .:..|:.|.|    |..||::...:.
  Fly   158 PV---DFQLTCPHLRRLVLNGVVMH------------HRLQFAHLHD----LGHLDLTSCVLANF 203

 Worm   383 KLDGIFKLKHLKVLWMRNLQFECSSDMLDLFKLTGLTALDVS-------RDVYKTNIKTIMQFVE 440
            .|:.:..|.:|..|.:.|: :..::.:..:..|..|..||:|       ...|....:|:...::
  Fly   204 SLEALGSLPNLHTLILFNV-WPIANQLHAICCLRRLCTLDISISSSGNGHGTYDLPDQTLEMLMD 267

 Worm   441 CGIILPNLTFLDASGTDLNEN--------LLNSLASHPKLQQIVAIDTNVQYIKTTGHEILSFGN 497
               .|.:||.||.|||:|..|        ..:.:...||::|..|: |::..:.:.....|.|
  Fly   268 ---NLRHLTHLDISGTNLAGNGVATKESTTTSGMQQSPKMEQHFAL-TDIPGLASRTQRPLQF-- 326

 Worm   498 LQTSLRILKHFVNLKRSVATRKCLLRITTQLKQFHNDTKQYDVVKCLRHAIEAIETF-RPNEQ-- 559
                                          |..:|  |..:   .|.||.|.|:|.. ..|||
  Fly   327 ------------------------------LGLYH--TAHW---ACKRHDIPALEVAGDANEQQI 356

 Worm   560 LKAEIRWNDNTYITGLNCLIEISRNKSHIF---HPLDAKLVLDILLIASERIL-----PLTSSAL 616
            |.|...::|...:     |..:..:..|:|   :..|....||::|.|.:|.|     .::.||
  Fly   357 LTAARYYHDRPVL-----LTRVLNDLYHLFRFENCKDIHTALDVVLSAMDRHLKFKHMQISGSA- 415

 Worm   617 QHPCQAVWEAIQNLVDQEFDWLDYDQIGTSAMRFALEVYLRPDRFL----------NQATSVVET 671
                 .::..::.....:|..|..:.|..:.:. .:|:::..|..|          :....|:..
  Fly   416 -----TLFYIVKGRDRSKFGALLRNHIIRTLLN-GMEMHITDDTMLRNGYLTLTQFHMPVDVLFE 474

 Worm   672 CTRL--------SPSQDFSGYLEKKLTTCVINLIKEEIINGNERQCISFLKIVYSM-TL----CS 723
            ..||        |.::. .|::: ::...::|.:..: ::|.::..:..|.:|.:| ||    .:
  Fly   475 YERLIKILLHGVSKTEQ-EGFVQ-RIAIYLLNTLACQ-VDGRQKLFLGELGVVSTMFTLIKDRLT 536

 Worm   724 KSACEDILKNGKFASLVWCLQ-----NC------NSDELHLEVLH-------VIRNL-----SIV 765
            :|..:|:::..  .|.:|.:.     ||      ...|..|:.||       ::||:     ::.
  Fly   537 RSVFDDVMEVA--WSTMWNVTDETAINCKRFLDGRGMEYFLKCLHTFPDRDELLRNMMGLLGNVA 599

 Worm   766 HKSSIFKKHFTATEFKVFHQLLNDW-----------------------TSNKAYNVFTI------ 801
            ....:..|..|....:||.:||:..                       ::|.||..|.:
  Fly   600 EVKWLRPKLMTQEFIEVFARLLDSLSDGIEVGGASASVVARVREREMASANHAYLRFQVSYNAAG 664

 Worm   802 ISLRIFSSERD-WTTCEFSSDANDLLIDR-----------------FRYFQPSEITEKVEIYLGI 848
            :...|.|...| ||   ..:.:.:.:::|                 :|.|:|  |...|..|
  Fly   665 VLAHIASDGADAWT---IKTPSREHVLERMVAAIQRWNIKSERNINYRSFEP--ILSLVRCY--- 721

 Worm   849 LEDVLKTSRLEGPVLWALLTL-QILTEQKKEFVET---IEEYSYILKH 892
                 :|.:.:...:|||..| |:..|:..:.||.   |:..:.:::|
  Fly   722 -----ETPQCQHWAVWALANLTQVYPEKYCKLVEQENGIQILNELIEH 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zeel-1	NP_490966.2	LRR	<317..>475	CDD:443914	36/177 (20%)
		leucine-rich repeat	346..370	CDD:275380	3/23 (13%)
		leucine-rich repeat	371..392	CDD:275380	5/22 (23%)
		leucine-rich repeat	393..417	CDD:275380	4/23 (17%)
		leucine-rich repeat	418..447	CDD:275380	7/35 (20%)
		leucine-rich repeat	448..471	CDD:275380	9/30 (30%)
CG12084	NP_612112.1	leucine-rich repeat	110..135	CDD:275381	4/24 (17%)
		leucine-rich repeat	136..167	CDD:275381	10/35 (29%)
		leucine-rich repeat	168..189	CDD:275381	3/32 (9%)
		LRR	<184..>282	CDD:443914	26/105 (25%)
		leucine-rich repeat	190..213	CDD:275381	5/22 (23%)