DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Y39A1A.17 and CG12084

DIOPT Version :9

Sequence 1:	NP_001366658.1	Gene:	Y39A1A.17 / 189711	WormBaseID:	WBGene00012655	Length:	207	Species:	Caenorhabditis elegans
Sequence 2:	NP_612112.1	Gene:	CG12084 / 192509	FlyBaseID:	FBgn0043458	Length:	793	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	48/215 - (22%)
Similarity:	70/215 - (32%)	Gaps:	78/215 - (36%)

- Green bases have known domain annotations that are detailed below.

Worm    18 LRSFVVGCEENTNQYTEKNEIDIIS----------------VLRKGLNNRSQQKLLHLGLNG--- 63
            |||..:|...:..||.|.||.:.:.                |:...|.......|.||.|..
  Fly   136 LRSLELGISSHLLQYAEPNEKEPVDFQLTCPHLRRLVLNGVVMHHRLQFAHLHDLGHLDLTSCVL 200

Worm    64 ---------------QLILRRDW--INKLNNM--LPSLRSFDMSNS---------QLDAKDFFRL 100
                           .|||...|  .|:|:.:  |..|.:.|:|.|         .|..:....|
  Fly   201 ANFSLEALGSLPNLHTLILFNVWPIANQLHAICCLRRLCTLDISISSSGNGHGTYDLPDQTLEML 265

Worm   101 CKNFPNLEFLDIRETGL----------STISGLNRLQNLQILKMQNMEFHNHFDIIDLFGLTK-- 153
            ..|..:|..|||..|.|          :|.||:          .|:.:...||.:.|:.||..
  Fly   266 MDNLRHLTHLDISGTNLAGNGVATKESTTTSGM----------QQSPKMEQHFALTDIPGLASRT 320

Worm   154 ---LKILDV------SCNRY 164
               |:.|.:      :|.|:
  Fly   321 QRPLQFLGLYHTAHWACKRH 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Y39A1A.17	NP_001366658.1	None
CG12084	NP_612112.1	leucine-rich repeat	110..135	CDD:275381
		leucine-rich repeat	136..167	CDD:275381	9/30 (30%)
		leucine-rich repeat	168..189	CDD:275381	2/20 (10%)
		leucine-rich repeat	190..213	CDD:275381	4/22 (18%)
		ARM	535..628	CDD:237987
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3665
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900