| Sequence 1: | NP_001336023.1 | Gene: | ECT2 / 1894 | HGNCID: | 3155 | Length: | 958 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_523965.2 | Gene: | pbl / 38879 | FlyBaseID: | FBgn0003041 | Length: | 1311 | Species: | Drosophila melanogaster |
| Alignment Length: | 1326 | Identity: | 315/1326 - (23%) |
|---|---|---|---|
| Similarity: | 491/1326 - (37%) | Gaps: | 540/1326 - (40%) |
- Green bases have known domain annotations that are detailed below.
|
Human 36 IGSTSYVEEEMPQIETRVILVQEAGKQEELIKALKTIKIMEVPVIKIKESCPGKSDEKLIKSVIN 100
Human 101 MDIKVGFVKMESVEEFEGLDSPEFENVFVVTDFQDSVFNDLYKADCRVIGPPVVLNCSQKGEPLP 165
Human 166 FSCRPLYCTSMMNLVLCFTGFRKKEELVRLVTLVHHMGGVIRKDFNSKVTHLVANCTQGEKFRVA 230
Human 231 VSLGTPIMKPEWIYKAWERRNEQDFYAAVDDFRNEFKVPPFQDCILSFLGFSDEEKTNMEEMTEM 295
Human 296 QGGKYLPLGDERCTHLV------------------------------------------------ 312
Human 313 ----------------------------------------------------------------- 312
Human 313 ---------------------VEENI--------------------------------------- 317
Human 318 -------------VKDLP----------------------------------------------- 322
Human 323 -----FEP--------------------------------------------------------- 325
Human 326 -------------------------------------------SKKLY----------------- 330
Human 331 ----------------------------------------------------------------- 330
Human 331 --------------------------------------VVKQEWFWGSIQ------MDARAGETM 351
Human 352 YLYEKANTPELKKSVSM-LSLNTPNSNRKRRRLKETLAQLSRETDVSPFPPRKRPSAEHSLSIGS 415
Human 416 LLDISN-------TPESSINYGDTPKSCTKSSKSSTPVPSKQSARWQVAKELYQTESNYVNILAT 473
Human 474 IIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHTKIKDDLEDLIVNWDESKSIGDIFLK 538
Human 539 YSKDLVKTYPPFVNFFEMSKETIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSV 603
Human 604 ALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSS 668
Human 669 HRSLVQRVETISLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPH-GQTRPPASLKHIHL 732
Human 733 MPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSDELPKENWLKMLCRHVANTICK 797
Human 798 ADAENLIYTADPESFEVNTKDMD-STLSRASRAIKKTSKKVTRAFSFSKTP---KRALRRALMTS 858
Human 859 HGSVEGRSPSSNDKHVMSRLSSTSSL 884 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ECT2 | NP_001336023.1 | PTCB-BRCT | 179..242 | CDD:315420 | 31/62 (50%) |
| BRCT | 266..341 | CDD:306918 | 28/532 (5%) | ||
| Nuclear localization signal | 378..382 | 3/3 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 388..449 | 14/67 (21%) | |||
| Nuclear localization signal | 401..405 | 1/3 (33%) | |||
| RhoGEF | 456..640 | CDD:214619 | 96/183 (52%) | ||
| PH_Ect2 | 631..804 | CDD:269936 | 64/173 (37%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 857..884 | 7/26 (27%) | |||
| pbl | NP_523965.2 | PTCB-BRCT | 117..180 | CDD:289507 | 31/62 (50%) |
| RhoGEF | 852..1032 | CDD:279015 | 96/179 (54%) | ||
| PH_Ect2 | 1023..1186 | CDD:269936 | 64/173 (37%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165150914 | |
| Domainoid | 1 | 1.000 | 201 | 1.000 | Domainoid score | I3011 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3524 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H7298 | |
| Inparanoid | 1 | 1.050 | 527 | 1.000 | Inparanoid score | I1234 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S5713 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D305707at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0007255 | |
| OrthoInspector | 1 | 1.000 | - | - | oto88607 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104055 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR16777 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3920 |
| SonicParanoid | 1 | 1.000 | - | - | X5358 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.740 | |||||