Protein Alignment ECHS1 and DCI1

DIOPT Version :10

• Sequence 1: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Sequence 2: NP_014823.3
• Gene: DCI1 / 854352
• SGDID: S000005706
• Length: 271
• Species: Saccharomyces cerevisiae
• Alignment Length: 261
• Identity: 59/261 - (22%)
• Similarity: 94/261 - (36%)
• Gaps: 73/261 - (27%)

Human    44 NNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAI-------------VLTGGDKAFA 95
            |....:|:|..||.||:|             |||:...:..:             ||....|.|:
Yeast    10 NGPFFIIKLIDPKHLNSL-------------TFEDFVYIALLLHKANDIDSVLFTVLQSSGKYFS 61

Human    96 AGADIKEMQNLSFQDCYS--------------------SKFLKHWDHLTQVKKPVIAAVNGYAFG 140
            :|.....:..|:..|..|                    :.|..|       ||.::..:||.|.|
Yeast    62 SGGKFSAVNKLNDGDVTSEVEKVSKLVSAISSPNIFVANAFAIH-------KKVLVCCLNGPAIG 119

Human   141 GGCELAMMCDIIYAGEKAQFAQ-PEILIGTIPGAGGTQRLTRAVGKSLAME------MVLTGDRI 198
            ....|..:|||:|:...:.|.. |...:|.:...|.:..||:.:|.:.|.|      .||..:.|
Yeast   120 LSASLVALCDIVYSQNDSVFLLFPFSNLGFVAEVGTSVTLTQKLGINSANEHMIFSTPVLFKELI 184

Human   199 SAQDAKQAGLVSKICPVETLVEEAIQCAEKIASN-----SKIVVAMAKESVNAAFEMTLTEGSKL 258
            .....|...|.:    .||..|:.:|   .|..|     .|.|:.| ||.:::..:..|.:...:
Yeast   185 GTIITKNYQLTN----TETFNEKVLQ---DIKQNLEGLYPKSVLGM-KELLHSEMKQKLIKAQAM 241

Human   259 E 259
            |
Yeast   242 E 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	59/261 (23%)
DCI1	NP_014823.3	crotonase-like	7..178	CDD:119339	41/187 (22%)