Protein Alignment ECHS1 and ECI1

DIOPT Version :10

• Sequence 1: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Sequence 2: NP_013386.1
• Gene: ECI1 / 850990
• SGDID: S000004274
• Length: 280
• Species: Saccharomyces cerevisiae
• Alignment Length: 240
• Identity: 54/240 - (22%)
• Similarity: 88/240 - (36%)
• Gaps: 37/240 - (15%)

Human    49 LIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDC-- 111
            :|.|..|..||||.......|.:.|:..:.:..|...::....:.|::|||.|.:......|.
Yeast    21 IIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNK 85

Human   112 YSSK------------------FLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA-GEK 157
            |.|:                  |:||       .|.:|..:||.|.|....|..:|||:|: .:|
Yeast    86 YPSETSKWVSNFVARNVYVTDAFIKH-------SKVLICCLNGPAIGLSAALVALCDIVYSINDK 143

Human   158 AQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEA 222
            .....|...:|.|...|.|..|....|.:...|.::...........:.|.:||...:.:...||
Yeast   144 VYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAEA 208

Human   223 IQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTF 267
            .        |:|::..: :|.|...:..:.....||.|......|
Yeast   209 F--------NAKVLEEL-REKVKGLYLPSCLGMKKLLKSNHIDAF 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	54/240 (23%)
ECI1	NP_013386.1	crotonase-like	11..219	CDD:119339	48/213 (23%)