Protein Alignment ECHS1 and echs1

DIOPT Version :10

• Sequence 1: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Sequence 2: NP_001005437.1
• Gene: echs1 / 448019
• XenbaseID: XB-GENE-5945792
• Length: 286
• Species: Xenopus tropicalis
• Alignment Length: 283
• Identity: 201/283 - (71%)
• Similarity: 249/283 - (87%)
• Gaps: 8/283 - (2%)

Human     8 LSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQA 72
            ||.:|..||        |.:::|:.|:||:.|::|:::.||||:||||||||||||||:.|:|||
 Frog    12 LSQIRQCLR--------RGYSAGSAFQYILVERKGQHHNVGLIRLNRPKALNALCDGLMTEINQA 68

Human    73 LKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGY 137
            |.||||||.:||||:||.::|||||||||||||.|||:||...||.||:.::.||||||||||||
 Frog    69 LDTFEEDPNIGAIVITGSERAFAAGADIKEMQNRSFQECYGGNFLSHWNRVSFVKKPVIAAVNGY 133

Human   138 AFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQD 202
            |.|||||||||||||||||||:|.|||||:||||||||||||||||||||||||||:|||||||:
 Frog   134 ALGGGCELAMMCDIIYAGEKAEFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLSGDRISAQE 198

Human   203 AKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTF 267
            |:|||||||:.||:::|::||.|.||||.|||::|::|||:|:||||::|.||::|||:||:|||
 Frog   199 AQQAGLVSKVYPVDSVVDQAIICGEKIARNSKLIVSIAKEAVSAAFELSLAEGNRLEKRLFHSTF 263

Human   268 ATDDRKEGMTAFVEKRKANFKDQ 290
            ||:|||||||||||||||||.|:
 Frog   264 ATEDRKEGMTAFVEKRKANFTDK 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	192/255 (75%)
echs1	NP_001005437.1	crotonase-like	28..286	CDD:474030	193/257 (75%)