Protein Alignment ECHS1 and CG5611

DIOPT Version :10

• Sequence 1: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Sequence 2: NP_651574.1
• Gene: CG5611 / 43318
• FlyBaseID: FBgn0039531
• Length: 326
• Species: Drosophila melanogaster
• Alignment Length: 255
• Identity: 74/255 - (29%)
• Similarity: 122/255 - (47%)
• Gaps: 32/255 - (12%)

Human     5 RVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDEL 69
            |:.|:.||.         |......||....::.|   |::.:.||.|||.:..|::.....::|
  Fly    21 RISLATVRN---------AESESQEGAPARTVLVE---KDSHITLIGLNREQQRNSIDANTAEQL 73

Human    70 NQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQ------NLSFQDCYSSKFLKHWDHL----T 124
            .:|:..||.|......||.|...:|.||.|::|::      :|:|       .|:|...:    .
  Fly    74 TEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNF-------LLRHEGSVGPTRR 131

Human   125 QVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAM 189
            .::||::..::|:...||.|||:|||:....:.|........:|.....|||.||..|||.|.|:
  Fly   132 HLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNAL 196

Human   190 EMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFE 249
            |::.||.||.:.:|::.|||:::....|.:.:|:..|..||   |..:|......||..|
  Fly   197 EIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIA---KFPMASLMHDRNAVLE 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	67/228 (29%)
CG5611	NP_651574.1	crotonase-like	39..256	CDD:474030	67/228 (29%)