Protein Alignment ECHS1 and Srlp

DIOPT Version :10

• Sequence 1: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Sequence 2: NP_650199.1
• Gene: Srlp / 41533
• FlyBaseID: FBgn0038049
• Length: 378
• Species: Drosophila melanogaster
• Alignment Length: 264
• Identity: 78/264 - (29%)
• Similarity: 125/264 - (47%)
• Gaps: 22/264 - (8%)

Human    28 ASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDK 92
            |..|..:.|:.|| .||.|  ||.:|||:..||:......:|..|...||.|......||.|...
  Fly    41 AEAAPPKNILVEK-DKNIT--LIGINRPQQRNAIDSLTASQLCDAFANFEADDTSPVAVLYGVGG 102

Human    93 AFAAGADIKEMQNLSFQDCYSSKFLKHWDHL----TQVKKPVIAAVNGYAFGGGCELAMMCDIIY 153
            :|.:|.||.|:.....::......::....:    .|:||||:..:|||....|.|||:|||:..
  Fly   103 SFCSGFDILEISTDEKEEISVDILMRPEGSVGPTRRQIKKPVVCGINGYCIANGLELALMCDLRV 167

Human   154 AGEKA-------QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSK 211
            ..|.|       :|..|.:..|||       ||...:|.|.|::::|||..:.:|:|...|||::
  Fly   168 MEESAVLGFFNRRFGVPMLDAGTI-------RLPAMIGLSRALDLILTGRPVGSQEAHDIGLVNR 225

Human   212 ICPVETLVEEAIQCAEKIASNSKIVVAMAKESV-NAAFEMTLTEGSKLEKKLFYSTFATDDRKEG 275
            |.|..|.:..|::.|..:|...:..:...:.|| ::.||.:....:...:.:|.|....:|.:.|
  Fly   226 IVPTGTALGNALELATCLAKFPQRALIHDRNSVYSSTFETSTFHQAVQNEVMFTSREIIEDMQNG 290

Human   276 MTAF 279
            :..|
  Fly   291 IKWF 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	76/260 (29%)
Srlp	NP_650199.1	crotonase-like	49..259	CDD:474030	68/219 (31%)