Protein Alignment ECHS1 and ech-6

DIOPT Version :10

• Sequence 1: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Sequence 2: NP_001366674.1
• Gene: ech-6 / 176376
• WormBaseID: WBGene00001155
• Length: 288
• Species: Caenorhabditis elegans
• Alignment Length: 264
• Identity: 161/264 - (60%)
• Similarity: 200/264 - (75%)
• Gaps: 1/264 - (0%)

Human    27 FASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGD 91
            |:|.|. |.|..||.|:...|.||:|||||||||||..|:.||..||:..:.|.:|||||:||.:
 Worm    26 FSSKAP-EMIKIEKVGEKQNVALIKLNRPKALNALCAQLMTELADALEVLDTDKSVGAIVITGSE 89

Human    92 KAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156
            :|||||||||||.|..|...:|..||.:|..::.|||||||||||:|.|||.|||||||||||||
 Worm    90 RAFAAGADIKEMTNNEFATTFSGSFLSNWTAVSDVKKPVIAAVNGFALGGGNELAMMCDIIYAGE 154

Human   157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEE 221
            ||:|.||||.||||||||||||..||.|||.|||:.|||:.::||:||:.|:||||.|.:.:|.|
 Worm   155 KARFGQPEINIGTIPGAGGTQRWARAAGKSFAMEVCLTGNHVTAQEAKEHGIVSKIFPADQVVGE 219

Human   222 AIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKAN 286
            |::..||||..|.::|.||||:||.|:|:||.||...|::||::||||.|||||||||.||||..
 Worm   220 AVKLGEKIADQSPLIVQMAKEAVNKAYELTLQEGLHFERRLFHATFATKDRKEGMTAFAEKRKPQ 284

Human   287 FKDQ 290
            ::.:
 Worm   285 WESK 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	158/255 (62%)
ech-6	NP_001366674.1	crotonase-like	32..284	CDD:474030	158/251 (63%)