DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chil-19 and Cht10

DIOPT Version :9

Sequence 1:	NP_496026.2	Gene:	chil-19 / 187736	WormBaseID:	WBGene00011162	Length:	452	Species:	Caenorhabditis elegans
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	106/434 - (24%)
Similarity:	182/434 - (41%)	Gaps:	100/434 - (23%)

- Green bases have known domain annotations that are detailed below.

Worm    62 GSANTSTVPNVSSTVAKSTITTRAPPVCNK--RIIGY------YFATQTSVITRDQVSKL-THAV 117
            ||...:..|.|......|.||  .||:.|.  :::.|      |.::|...:..|..:.| ||.:
  Fly  1879 GSNQRTQEPAVHRPNPTSVIT--EPPIINNSYKVVCYFTSWAWYRSSQGKFVPEDIDANLCTHLI 1941

Worm   118 FAFVNM--------TSDGHLQIDGDLAKNRFTNLIEIAKQQTPQVKVMISIGG-NDN--SNNFKP 171
            :.|..:        |.|....||     |||...:...||:  .::||::||| ||:  |...:.
  Fly  1942 YGFAVLDSKSLTIKTHDSWTDID-----NRFYERVVEYKQR--GLRVMLAIGGWNDSLGSKYARL 1999

Worm   172 GLSSPDRKKLFINSTVSFLQTYDIDGVDLYWKWP----------GKTSKDIYSQFINDLRYSLQR 226
            .|:|..|:: |:.|.:|||:.:..:|:||.|::|          ..|.||.:...:.:|..:.
  Fly  2000 VLNSQSRRR-FVASVISFLEQHGFEGLDLAWEFPVCWQVNCNRGNPTEKDGFVALVKELSEAF-- 2061

Worm   227 QKRNYIMSIVLPPPDMGANYEAGIDIENIFDNVDFLNIFTMGYFGPWQNDAGMITGAASQLFNG- 290
            ::...|:|..:.|..|  ..:||.::..:....|::.:.|..:.|.|.    |.||..:.||:.
  Fly  2062 KENGLILSAAVSPSKM--VIDAGYNVFELSPYFDWVAVMTYDFHGHWD----MRTGQIAPLFHRG 2120

Worm   291 ------VNGVPGRKTYNIHHSTERYVCKTGQSDKYNIAIPFYTM---LWKHVKGPVNPPNIEIYR 346
                  :||     .::||:..||.:    .:||..:.:|.|..   |....:..:|...:...:
  Fly  2121 GDENLYLNG-----NFSIHYWLERGI----PNDKLVMGMPMYGQTFTLADQNRRSLNDKTVGPGK 2176

Worm   347 NATF--QGGVVGETSMSRKLV--------QEEGYDFSNPTYNPEIRAAFKYNATTETFLTFETND 401
            ..||  ..|.:....:..|:|        .|||           |..::.|:.  ..:::::...
  Fly  2177 AGTFTRADGFLAYYEICEKVVNDDWKVVRDEEG-----------IFGSYAYSG--NQWISYDDVT 2228

Worm   402 TIAAKIDYVKDRILGGVWIWAVDMDDDSNNLLNLVKFTGYCTVG 445
            ||..|..::|...|||..|||:|:||          |.|.|..|
  Fly  2229 TIRRKSQFIKSLQLGGGMIWALDLDD----------FRGLCGCG 2262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chil-19	NP_496026.2	Glyco_18	92..426	CDD:214753	90/381 (24%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753	90/381 (24%)
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351	96/401 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164213
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740