DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment chil-16 and Cht10

DIOPT Version :9

Sequence 1:NP_496020.1 Gene:chil-16 / 187732 WormBaseID:WBGene00011158 Length:440 Species:Caenorhabditis elegans
Sequence 2:NP_001036422.1 Gene:Cht10 / 3355116 FlyBaseID:FBgn0250907 Length:2286 Species:Drosophila melanogaster


Alignment Length:410 Identity:92/410 - (22%)
Similarity:174/410 - (42%) Gaps:71/410 - (17%)


- Green bases have known domain annotations that are detailed below.


 Worm    61 EHQEILYQLSTVKPDPINTKNRDYKKRIVGYY-----YRNGNDSIMMGQLAK--LTHAVFAFLEL 118
            ||:.||.....::.:.|.......:.:|:.|:     ||.|....:...:..  .||.::.|..|
  Fly  1384 EHEGILDPNHVLEEENIEATEMATEFKIICYFTNWAWYRQGGGKFLPEDIDSDLCTHIIYGFAVL 1448

 Worm   119 HPDG-TIHFESRKAKESFLYLRKLASILKFDAKIMFSIGG--PANTQFFSPIIQNEEMKRKFIDS 180
            ..|. ||......|.....:..::.:..|..||:..:|||  .:....:|.:::|.|.:.:||.:
  Fly  1449 SRDNLTIQPHDSWADLDNKFYERIVAYRKKGAKVTVAIGGWNDSAGDKYSRLVRNPEARSRFIRN 1513

 Worm   181 IIYFLKQYKLDGVDLFWKW----------SSSGDKFTYSSFLQELKHKLRSHRQNYIISIVLPPA 235
            ::.|:::|..||:||.|::          .::.:|..:|:.::||.:..:.  :..|:|..:.| 
  Fly  1514 VLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALVRELFYAFQP--RGLILSAAVSP- 1575

 Worm   236 GVDTWELGYDLEEIMEHVDFMNVYSMDYSGPWDNQWGTPTGPSAPLAFNIGPRKNFNVDWTMKYY 300
            .....:.||::.|:..:..:::|.:.||.|.||.:    ||..||:..:.....|||.:::|.|:
  Fly  1576 NKKVIDAGYEVAELSHYFSWISVMAYDYHGQWDKK----TGHVAPMYSHPEGTANFNANFSMNYW 1636

 Worm   301 SCKTQQPGKFNMVIPFYARYWNNVQEAVDPRTEVFRNAEIRNNRADGVPYMDRSSADYKMA---- 361
            ........|..|.||.|.              :.|..||...::.:...|....:.:...|    
  Fly  1637 ISMGADRRKLVMGIPLYG--------------QSFSLAETTKHQLNAPTYGGGEAGEATRARGFL 1687

 Worm   362 ------------SWDNLTST-----PYIWKPDERRFFTFENQKSIAIKTRYAIDMNLGGVWIWSV 409
                        .|:.:..|     |:.:..|:  :.:|::...|..|:.|...|.|||..||::
  Fly  1688 AYYEICLKIRHHRWNVVRDTKGRIGPFAYHGDQ--WVSFDDVPMIRHKSEYIKAMGLGGAMIWAL 1750

 Worm   410 DMGDHGNV-------LLSAV 422
            |:.|..||       ||.|:
  Fly  1751 DLDDFKNVCECESYPLLKAI 1770

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chil-16NP_496020.1 Glyco_18 87..411 CDD:214753 80/364 (22%)
Cht10NP_001036422.1 Glyco_18 220..565 CDD:214753
GH18_chitolectin_chitotriosidase 221..586 CDD:119351
ChtBD2 697..737 CDD:214696
CBM_14 801..848 CDD:279884
CBM_14 875..918 CDD:279884
Glyco_18 966..1310 CDD:214753
GH18_chitolectin_chitotriosidase 967..1331 CDD:119351
Glyco_18 1410..1753 CDD:214753 81/365 (22%)
GH18_chitolectin_chitotriosidase 1411..1774 CDD:119351 87/383 (23%)
ChtBD2 1834..1871 CDD:214696
Glyco_18 1909..2253 CDD:214753
GH18_chitolectin_chitotriosidase 1910..2274 CDD:119351
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160164225
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG3325
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm4747
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.740

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