DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pknox1 and achi

DIOPT Version :9

Sequence 1:	NP_057879.2	Gene:	Pknox1 / 18771	MGIID:	1201409	Length:	436	Species:	Mus musculus
Sequence 2:	NP_001286352.1	Gene:	achi / 36373	FlyBaseID:	FBgn0033749	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	228	Identity:	58/228 - (25%)
Similarity:	93/228 - (40%)	Gaps:	58/228 - (25%)

- Green bases have known domain annotations that are detailed below.

Mouse   227 QALSPGTIRIQN-------SQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGH 284
            |:...|..::||       |:..:.:|          ||.:.:||.|||.:..:::.||::|..:
  Fly    64 QSTEHGANQVQNYHDMMVDSEHHIDIN----------GSLRKRRGNLPKTSVKILKRWLYEHRYN 118

Mouse   285 PYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPML-------------------DSSCSETP 330
            .||::.||..::.:.|||:|||.|||||||||||..|:                   ..:||.:.
  Fly   119 AYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRREGNDPLHFTISRRGKKVSPNCSRSS 183

Mouse   331 K-----TKKKPAQNRPVQRFWPDSLASGVAQATPSELAMSEGAVVTITT-------PVNMNVDSL 383
            .     |...||...|.     ..:..|..:.......:.||....:|.       | |..:..:
  Fly   184 ALGANLTGPNPAHGSPA-----SEVVVGATEEVDGAGEIHEGIANVLTNFEQYVQGP-NGQMVKM 242

Mouse   384 QSLSSDGATLAVQQVM----MAGQSEDESVDST 412
            :....|....:.||.:    |..||...|:.:|
  Fly   243 EPEYEDSVIYSWQQAIANNPMGFQSLHSSLQAT 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pknox1	NP_057879.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..50
		Meis_PKNOX_N	80..165	CDD:374576
		Homeobox_KN	277..316	CDD:368670	20/38 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..436		4/12 (33%)
achi	NP_001286352.1	Homeobox_KN	111..150	CDD:283551	20/38 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842732
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740