| Sequence 1: | NP_032887.3 | Gene: | Pkd2 / 18764 | MGIID: | 1099818 | Length: | 966 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_648970.2 | Gene: | brv2 / 39932 | FlyBaseID: | FBgn0036712 | Length: | 736 | Species: | Drosophila melanogaster |
| Alignment Length: | 774 | Identity: | 171/774 - (22%) |
|---|---|---|---|
| Similarity: | 300/774 - (38%) | Gaps: | 157/774 - (20%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 170 DPLHRHLPLEGQP--PRVAWAERLVRGLRGLWGTRLMEESNAN---REKYLKSVLRELVTYLFFL 229
Mouse 230 VVLCILTYGMMSSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQ 294
Mouse 295 TSNHTQADNRSFIFYEN-------LLLGVPRLRQLRVRNGSCSIPQDLRDEI-KECYDVYSVSSE 351
Mouse 352 DRAPFGPRNGTA--W-----MYTSEKE---LNG----SSHWGIIASY-SGAGYYLDLSRTREETA 401
Mouse 402 AQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTA 466
Mouse 467 FDFFLAACEIIFCFFIIYYVVEEILEIR------IHRLSYFRSFWNCLDVVIVVLSVVAMVINIY 525
Mouse 526 RMSNAEGLLQFLE--DQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTM 588
Mouse 589 SRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIIL---GDINFAEIEEA 650
Mouse 651 NRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKL 715
Mouse 716 KRNTVDAISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDL 780
Mouse 781 EKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVD 845
Mouse 846 -RMEHSIGSIVSKIDAVI-VKLEIMERAKLKRREVLGRLLDGVAEDARLGRDSEIHREQ 902 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pkd2 | NP_032887.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..106 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 147..179 | 3/8 (38%) | |||
| PKD_channel | 265..685 | CDD:285288 | 106/453 (23%) | ||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:Q13563 | 639..641 | 0/4 (0%) | |||
| EFh | 730..776 | CDD:298682 | 11/45 (24%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 764..828 | 11/63 (17%) | |||
| Linker. /evidence=ECO:0000250|UniProtKB:Q13563 | 801..820 | 3/18 (17%) | |||
| Important for interaction with PACS1 and PACS2. /evidence=ECO:0000250|UniProtKB:Q13563 | 808..819 | 1/10 (10%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 914..966 | ||||
| brv2 | NP_648970.2 | PKD_channel | 169..596 | CDD:285288 | 106/456 (23%) |
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3599 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||