Protein Alignment Prkaca and Pka-C1

DIOPT Version :9

• Sequence 1: NP_032880.1
• Gene: Prkaca / 18747
• MGIID: 97592
• Length: 351
• Species: Mus musculus
• Sequence 2: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 353
• Identity: 288/353 - (81%)
• Similarity: 315/353 - (89%)
• Gaps: 2/353 - (0%)

Mouse     1 MGNAAAA--KKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKH 63
            |||.|..  ||....|:|||||.:|||:|..||.....|||.||.|:||||||||||||||:|:|
  Fly     1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQH 65

Mouse    64 KESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGE 128
            |.:.::||||||||||||||||:||||||||||||:.|||||.|.:.||||||||||:|||.|||
  Fly    66 KPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGE 130

Mouse   129 MFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
            ||||||::|||||||:|||||||||.|||||.||||||||||||||||.|||::|||||||||||
  Fly   131 MFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVK 195

Mouse   194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRF 258
            |||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
  Fly   196 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRF 260

Mouse   259 PSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPG 323
            ||||.||||||||||||||||||:||||.|||||||.||||:||||||:|:|:||||||:.||||
  Fly   261 PSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPG 325

Mouse   324 DTSNFDDYEEEEIRVSINEKCGKEFTEF 351
            |||||||||||.:|:|..|||.|||.||
  Fly   326 DTSNFDDYEEEALRISSTEKCAKEFAEF 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prkaca	NP_032880.1	STKc_PKA	42..331	CDD:271111	251/288 (87%)
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	251/288 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	477	1.000	Domainoid score	I423
eggNOG	1	0.900	-	-		E1_KOG0616
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	601	1.000	Inparanoid score	I941
Isobase	1	0.950	-	0	Normalized mean entropy	S234
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	1	1.000	-	-		FOG0000539
OrthoInspector	1	1.000	-	-		otm43967
orthoMCL	1	0.900	-	-		OOG6_100326
Panther	1	1.100	-	-	LDO	PTHR24353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R632
SonicParanoid	1	1.000	-	-		X747
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.810