Protein Alignment Pitx3 and ey

DIOPT Version :9

• Sequence 1: XP_006526827.1
• Gene: Pitx3 / 18742
• MGIID: 1100498
• Length: 388
• Species: Mus musculus
• Sequence 2: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Alignment Length: 428
• Identity: 99/428 - (23%)
• Similarity: 141/428 - (32%)
• Gaps: 179/428 - (41%)

Mouse   121 GQEHSDSEKASASLPGGSPEDGS---LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIA 182
            |....::....||..|.:.:|.:   ||:|.:|.||.||:.|:..||..|:|..|||:..||.:|
  Fly   441 GSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLA 505

Mouse   183 VWTNLTEARVRVWFKNRRAKWRKRE--RSQQ-------------------------------AEL 214
            ....|.|||::|||.|||||||:.|  |:|:                               :.|
  Fly   506 GKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSL 570

Mouse   215 CKG-----------GFAAP-----------LGGLVPPYEEVYP---------------------- 235
            ..|           |.::|           ||..:...|...|
  Fly   571 LSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCR 635

Mouse   236 ----------------------GYSYGNWPPKALAPPLAAKTFPF-------------------- 258
                                  |::.|:....|::|.|...:..|
  Fly   636 RVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGA 700

Mouse   259 -----AFNSVNVGPLASQPVFSPPSSI--AASMVPS--------------AAAAPGTVPGPG--- 299
                 :||...|||||      |||.|  ...:.||              |.|....|||.|
  Fly   701 VTPIPSFNHSAVGPLA------PPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHHHIVPGDGGRP 759

Mouse   300 ALQGLG-------GA---------------PPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVY 342
            |..|||       ||               ||   |...||.|....:::|::|:|.......:.
  Fly   760 AGVGLGSGQSANLGASCSGSGYEVLSAYALPP---PPMASSSAADSSFSAASSASANVTPHHTIA 821

Mouse   343 RDPCNSSLASLRLKAKQHAS--FSYPAVPGPPPAANLS 378
            ::.|.|..:|.......|:|  .|.|..|.....|::|
  Fly   822 QESCPSPCSSASHFGVAHSSGFSSDPISPAVSSYAHMS 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pitx3	XP_006526827.1	Homeobox	152..205	CDD:365835	28/52 (54%)
		PTZ00395	<228..>322	CDD:185594	39/203 (19%)
		OAR	344..361	CDD:367680	3/16 (19%)
ey	NP_001014693.1	PAX	98..221	CDD:128645
		Homeobox	475..527	CDD:278475	27/51 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940