Protein Alignment Pitx3 and Ptx1

DIOPT Version :9

• Sequence 1: XP_006526827.1
• Gene: Pitx3 / 18742
• MGIID: 1100498
• Length: 388
• Species: Mus musculus
• Sequence 2: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Alignment Length: 282
• Identity: 123/282 - (43%)
• Similarity: 153/282 - (54%)
• Gaps: 68/282 - (24%)

Mouse   136 GGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRR 200
            |..|::....|:|||||||||||||||||.||.||||||||||||||:|||||||||||||||||
  Fly   252 GEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRR 316

Mouse   201 AKWRKRER-SQQAELCKGGFAAPLG-GLVPPY--EEVYPGYSYGNWPPKALAPPLAAKTFPFAFN 261
            |||||||| :..|.:....|.:..| ..:.|:  :.:|..|.|.||  ..:..||..|.||:..|
  Fly   317 AKWRKRERNAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNW--TKVPSPLGTKPFPWPVN 379

Mouse   262 SVNVGPLASQPV----------FSPPSSIAASMVPSAAAAPGTV-------PGPGALQGLGGAPP 309
                 ||.|...          |:..:|..|..:.:|:..||::       ...||:    |||
  Fly   380 -----PLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAV----GAP- 434

Mouse   310 GLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYR---DPC-----NSSLASLRLKAKQHAS--FS 364
                         |||.:.|        :||:||   :||     :||:|:||||||||||  |.
  Fly   435 -------------CPYTTPA--------NPYMYRSAAEPCMSSSMSSSIATLRLKAKQHASAGFG 478

Mouse   365 YP-AVPGPPPAAN---LSPCQY 382
            .| :.|.|...:|   ||.|||
  Fly   479 SPYSAPSPVSRSNSAGLSACQY 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pitx3	XP_006526827.1	Homeobox	152..205	CDD:365835	49/52 (94%)
		PTZ00395	<228..>322	CDD:185594	26/112 (23%)
		OAR	344..361	CDD:367680	12/21 (57%)
Ptx1	NP_001138130.2	Homeobox	268..320	CDD:278475	48/51 (94%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I5928
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1432356at2759
OrthoFinder	1	1.000	-	-		FOG0001767
OrthoInspector	1	1.000	-	-		otm42671
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45882
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X469
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.020