DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Etv4 and pnt

DIOPT Version :9

Sequence 1:	XP_006532521.1	Gene:	Etv4 / 18612	MGIID:	99423	Length:	533	Species:	Mus musculus
Sequence 2:	NP_524461.2	Gene:	pnt / 42757	FlyBaseID:	FBgn0003118	Length:	718	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	98/343 - (28%)
Similarity:	138/343 - (40%)	Gaps:	97/343 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse   175 SAYDSPRQIAIKSPAPGAPGQSPLQPFS--------------RAEQQQSLLRASSSSQSHPGHGY 225
            |:|..|..:|...   |..|..|....|              .|:..||...:..:.......|.
  Fly   455 SSYGLPAHLAAYG---GGSGSGPTGGRSSGGGGDESDYHSTISAQDHQSQQSSGGNGSGGASGGS 516

Mouse   226 LGEHSSVFQQPVDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQNFKQEYHDPLYEQAGQPA 290
            .|..:.......:...|:     .||......|..:.:    ||..|:|:        ....||.
  Fly   517 TGNSNGYLDSSSEFYGSY-----AGRNRFHDGYPPEFT----PYDAQSFQ--------SMGPQPT 564

Mouse   291 SSQ--GGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPSPGDGVMGYGYEKSLR 353
            :..  |....|::|.|                       |:...|..     .|::| ||
  Fly   565 AMDQWGAAHAHQHPAA-----------------------YMSTLGLD-----KGLLG-GY----- 595

Mouse   354 PFPDDVCIVPEKFEGDIKQEGIGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEF 418
                            ..|.|:      |.:...|.:||||||:.||.|.|...||:|||.|.||
  Fly   596 ----------------TTQGGV------PCFTGSGPIQLWQFLLELLLDKTCQSFISWTGDGWEF 638

Mouse   419 KLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPD 483
            ||.:|:||||.|||:||:|.|||:||||.|||||:|.|:.|.||:||||:|||:.:.|.... |:
  Fly   639 KLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQNLVGHT-PE 702

Mouse   484 NQRPALKAEFDRPVSEED 501
            .    |.|::|..:.::|
  Fly   703 E----LVAKYDLKIEKKD 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Etv4	XP_006532521.1	ETS_PEA3_N	54..388	CDD:368026	36/228 (16%)
Etv4	XP_006532521.1	ETS	390..473	CDD:197710	55/82 (67%)
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879
pnt	NP_524461.2	ETS	609..693	CDD:197710	55/83 (66%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810