Protein Alignment TOR1A and Tor1a

DIOPT Version :10

• Sequence 1: NP_000104.1
• Gene: TOR1A / 1861
• HGNCID: 3098
• Length: 332
• Species: Homo sapiens
• Sequence 2: NP_695215.2
• Gene: Tor1a / 266606
• RGDID: 628863
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 333
• Identity: 305/333 - (91%)
• Similarity: 322/333 - (96%)
• Gaps: 1/333 - (0%)

Human     1 MKLGRAVLGLLLLAPSVVQAVEPISLGLALAGVLTGYI-YPRLYCLFAECCGQKRSLSREALQKD 64
            ||||||.|.||||.|.||:||||||||||||||||||| ||||||||||||||||||||||||||
  Rat     1 MKLGRATLALLLLVPCVVRAVEPISLGLALAGVLTGYISYPRLYCLFAECCGQKRSLSREALQKD 65

Human    65 LDDNLFGQHLAKKIILNAVFGFINNPKPKKPLTLSLHGWTGTGKNFVSKIIAENIYEGGLNSDYV 129
            ||:.||||||||::|||||.||::||||||||||||||||||||||.||||||||||||||||||
  Rat    66 LDNKLFGQHLAKRVILNAVSGFLSNPKPKKPLTLSLHGWTGTGKNFASKIIAENIYEGGLNSDYV 130

Human   130 HLFVATLHFPHASNITLYKDQLQLWIRGNVSACARSIFIFDEMDKMHAGLIDAIKPFLDYYDLVD 194
            |||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||:||
  Rat   131 HLFVATLHFPHASNITLYKDQLQMWIRGNVSACARSIFIFDEMDKMHAGLIDAIKPFLDYYDVVD 195

Human   195 GVSYQKAMFIFLSNAGAERITDVALDFWRSGKQREDIKLKDIEHALSVSVFNNKNSGFWHSSLID 259
            .||||||:|||||||||||||||||||||||||||:|||:|:||||:||||||||||||||||||
  Rat   196 EVSYQKAIFIFLSNAGAERITDVALDFWRSGKQREEIKLRDMEHALAVSVFNNKNSGFWHSSLID 260

Human   260 RNLIDYFVPFLPLEYKHLKMCIRVEMQSRGYEIDEDIVSRVAEEMTFFPKEERVFSDKGCKTVFT 324
            ||||||||||||||||||||||||||||||||.||||:::||||||||||||:||||||||||||
  Rat   261 RNLIDYFVPFLPLEYKHLKMCIRVEMQSRGYEEDEDIINKVAEEMTFFPKEEKVFSDKGCKTVFT 325

Human   325 KLDYYYDD 332
            |||||.||
  Rat   326 KLDYYLDD 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TOR1A	NP_000104.1	Torsin	55..169	CDD:399367	104/113 (92%)
		Interaction with SNAPIN	91..251		150/159 (94%)
		Interaction with KLC1. /evidence=ECO:0000269|PubMed:14970196	251..332		74/80 (93%)
		Interaction with SYNE3. /evidence=ECO:0000269|PubMed:18827015	312..332		17/19 (89%)
Tor1a	NP_695215.2	Torsin	56..170	CDD:399367	104/113 (92%)
		Interaction with SNAPIN. /evidence=ECO:0000250	92..252		150/159 (94%)
		Interaction with KLC1. /evidence=ECO:0000250	252..333		74/80 (93%)
		Interaction with SYNE3. /evidence=ECO:0000250	313..333		17/19 (89%)