DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdgfrb and drpr

DIOPT Version :9

Sequence 1:	NP_001139740.1	Gene:	Pdgfrb / 18596	MGIID:	97531	Length:	1099	Species:	Mus musculus
Sequence 2:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster

Alignment Length:	110	Identity:	27/110 - (24%)
Similarity:	49/110 - (44%)	Gaps:	22/110 - (20%)

- Green bases have known domain annotations that are detailed below.

Mouse   964 EGYK---KKYQQV---DEEFLRSDHPAILR-SQARFPGIHSLRSPLDTSSVLYTAVQPNESDNDY 1021
            ||||   |.|.::   ::|:   ||....| |.::.|..|.:...:  .::.....:|:...|..
  Fly   941 EGYKDPVKIYSKILFPEDEY---DHLDYSRPSTSQKPHYHRMNDAM--LNINQDEEKPSNVKNMT 1000

Mouse  1022 II---PLPDPKPDVADEGLPEGSPSLASSTLNEVNTSSTISCDSP 1063
            ::   |||..:|:...|....     .::.|:.|:|:|..|  ||
  Fly  1001 VLLNKPLPPTEPEPQHECFDN-----TNTNLDNVSTASPSS--SP 1038

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdgfrb	NP_001139740.1	ig	36..113	CDD:278476
		IG_like	221..309	CDD:214653
		Ig	227..311	CDD:299845
		Ig	313..414	CDD:299845
		IG	334..412	CDD:214652
		PKc_like	562..953	CDD:304357
		Pkinase_Tyr	600..953	CDD:285015
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1017..1099		13/50 (26%)
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900