DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pdgfra and Cad96Ca

DIOPT Version :9

Sequence 1:NP_001076785.1 Gene:Pdgfra / 18595 MGIID:97530 Length:1089 Species:Mus musculus
Sequence 2:NP_651349.1 Gene:Cad96Ca / 43026 FlyBaseID:FBgn0022800 Length:773 Species:Drosophila melanogaster


Alignment Length:413 Identity:134/413 - (32%)
Similarity:200/413 - (48%) Gaps:102/413 - (24%)


- Green bases have known domain annotations that are detailed below.


Mouse   585 RWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMT 649
            ||||||..|....|||.||||:|....|..::.::.:..||||.||.:|...:::.|:|||::|.
  Fly   462 RWEFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMK 526

Mouse   650 HLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSQHPEKPKKDLDIFGLNPAD 714
            .|.||:|:|:|||.||...|.::|.||...|.|..||..:|                        
  Fly   527 SLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSR------------------------ 567

Mouse   715 ESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVK 779
             :.|.|        |:                                                 
  Fly   568 -AERHY--------GN------------------------------------------------- 574

Mouse   780 NLLSDDDSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIM 844
               :...|..||..||.||.||||:||::|.|:..:||||||||:|:......|:.|||.|||::
  Fly   575 ---THGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVI 636

Mouse   845 HDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKI 909
            ....|..|....||::|||.||::||:::..||:||:|||:|||.:||.|||||:.. :....|:
  Fly   637 TSKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISA-ADVMRKV 700

Mouse   910 KSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDH 974
            :.|||:.||:|...|:|.||..||:.:|::||.|..:.::::.||         ...:|:::.: 
  Fly   701 RDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLL---------HTEMDYIELE- 755

Mouse   975 PAVARMRVDSDNAYIGVTYKNEE 997
                  |....|.|..|:...|:
  Fly   756 ------RFPDHNYYNIVSLSGEK 772

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PdgfraNP_001076785.1 Ig_3 28..100 CDD:372822
Ig_PDGFR-alphabeta 228..311 CDD:143269
Ig4_PDGFR 313..413 CDD:143267
Ig_TrkABC_d4 416..497 CDD:143173
PTKc_PDGFR_alpha 555..956 CDD:173653 128/370 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1018..1089
Cad96CaNP_651349.1 Cadherin_repeat 65..164 CDD:206637
STYKc 470..741 CDD:214568 120/356 (34%)
PTKc 474..742 CDD:270623 119/353 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24416
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.910

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