Protein Alignment Cdk18 and Eip63E

DIOPT Version :9

• Sequence 1: NP_032821.1
• Gene: Cdk18 / 18557
• MGIID: 97518
• Length: 451
• Species: Mus musculus
• Sequence 2: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Alignment Length: 489
• Identity: 223/489 - (45%)
• Similarity: 294/489 - (60%)
• Gaps: 63/489 - (12%)

Mouse     4 MKNFKRRLSLSVPRPETIEESLAEFTEQFNQLHTQ-------------------TNEDGTD--EP 47
            ::..|:|||.|..|.....|...|.|...:..|..                   .:|:..|  ||
  Fly    30 LQKLKKRLSHSFGRLTISREDGDESTHHHHHHHHHRGGHGGHHNHGNKVPYNGYNSEEYLDRLEP 94

Mouse    48 EQLSPGMQYQQRQNQRRFSMEDLNK------------------RLSLPMDIRLPQEFLQK----- 89
            ....|..:...|...:..:..|.||                  :||:..|.:|..|.:::
  Fly    95 NGNIPADKTNCRYGAQESAKNDNNKPQDWRSTDSTDHHDRVQRQLSVSSDSKLLDEDIREEMKYH 159

Mouse    90 ----LQLENPGLPKPLTRMS------RRASLSDIG----FGKLETYVKLDKLGEGTYATVFKGRS 140
                ::.:.|..||....::      ||...|..|    |||.|.||||:.||||:||||:||.|
  Fly   160 SHVVMRPKKPPRPKSEVFLNKQETHPRRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFS 224

Mouse   141 KLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQ 205
            |||...||||||||:.|||||.|||||.||||:|||:|||||||::||..:||.||||:::||.|
  Fly   225 KLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQ 289

Mouse   206 YLD-HCGNLMNMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSV 269
            |:: |.|.| :..||::|:|||||||:|||.|::||||:|||||||::.||||||||||||||||
  Fly   290 YMEKHPGGL-DHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSV 353

Mouse   270 PTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPG-STVKEELHLIFRL 333
            |:.|||:|||||||||||||||||||||.:||||||||..||.||.|.||| ....::|..||:|
  Fly   354 PSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKL 418

Mouse   334 LGTPTEESWPGVTSISEFRAYNFPRYLPQPLLSHAPRL--DTEGINLLSSLLLYESKSRMSAEAA 396
            ||||||::|||||....::.:....|.|:.|..:.|||  ..||..:.:..|....:.|:.|:.|
  Fly   419 LGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDA 483

Mouse   397 LNHPYFQSLGDRVHQLHDTASIFSLKEIQLQKDP 430
            |.||||..|..::::|.|..|||:::.:||..:|
  Fly   484 LQHPYFAQLPKKLYELPDETSIFTVEGVQLYTEP 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk18	NP_032821.1	PKc_like	115..402	CDD:304357	181/290 (62%)
		PLN00009	118..407	CDD:177649	181/292 (62%)
Eip63E	NP_001261373.1	PLN00009	203..492	CDD:177649	180/289 (62%)
		STKc_PCTAIRE_like	204..489	CDD:270835	177/285 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820