| Sequence 1: | XP_011249120.1 | Gene: | Furin / 18550 | MGIID: | 97513 | Length: | 803 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_727963.1 | Gene: | Fur2 / 32604 | FlyBaseID: | FBgn0004598 | Length: | 1682 | Species: | Drosophila melanogaster |
| Alignment Length: | 838 | Identity: | 366/838 - (43%) |
|---|---|---|---|
| Similarity: | 428/838 - (51%) | Gaps: | 222/838 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 27 QKIFTNTWAVHIPGGPAVADRVAQKHGFHNLGQI--FGDYYHFWHRAVTKRSLSPHRPRHSRLQR 89
Mouse 90 EPQVKWLEQQVAKRRAKRD-VYQE-PT-------------------------------------- 114
Mouse 115 -----------DPKFPQQWYL--------SGVTQRDLNVKEAWAQGFTGHGIVVSILDDGIEKNH 160
Mouse 161 PDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGAPL 225
Mouse 226 FPPPLRPGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQ 290
Mouse 291 GRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGN 355
Mouse 356 Q-NEKQIVTTDLRQK------CTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKP 413
Mouse 414 AHLNADD-WATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIVEILVEPKDI----GK 473
Mouse 474 RLEVRKAVTACLGEPNHITRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGF 538
Mouse 539 NDWAFMTTHSWDEDPAGEWVLEIEN--TSEANNYGTLTKFTLVLYGT------------------ 583
Mouse 584 --------------------APEG----------------------------------------- 587
Mouse 588 -----------------LSTPPE-----------------SSGCKTLTSSQACVVCEEGYSLHQK 618
Mouse 619 SCVQHCPPGFIPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCLSC-PSH 675 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Furin | XP_011249120.1 | S8_pro-domain | 33..107 | CDD:374560 | 35/75 (47%) |
| Peptidases_S8_Protein_convertases_Kexins_Fur in-lik | 113..412 | CDD:173789 | 205/362 (57%) | ||
| P_proprotein | 494..580 | CDD:366670 | 41/87 (47%) | ||
| FU | 591..629 | CDD:214589 | 17/54 (31%) | ||
| FU | 648..>685 | CDD:214589 | 14/29 (48%) | ||
| Fur2 | NP_727963.1 | S8_pro-domain | 242..318 | CDD:293079 | 35/75 (47%) |
| Peptidases_S8_Protein_convertases_Kexins_Fur in-like | 375..674 | CDD:173789 | 203/313 (65%) | ||
| Peptidase_S8 | 411..700 | CDD:278510 | 201/300 (67%) | ||
| P_proprotein | 761..849 | CDD:279782 | 41/87 (47%) | ||
| Furin-like | 966..1126 | CDD:279142 | 30/93 (32%) | ||
| FU | 970..1013 | CDD:238021 | 16/60 (27%) | ||
| FU | 1017..1067 | CDD:238021 | 13/24 (54%) | ||
| FU | 1063..1106 | CDD:214589 | |||
| GF_recep_IV | 1068..1232 | CDD:291509 | |||
| FU | 1116..1163 | CDD:238021 | |||
| FU | 1211..1255 | CDD:214589 | |||
| FU | 1259..1301 | CDD:214589 | |||
| FU | 1304..1348 | CDD:214589 | |||
| FU | 1356..1403 | CDD:238021 | |||
| FU | 1401..1444 | CDD:214589 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 40 | 1.000 | Domainoid score | I12484 |
| eggNOG | 1 | 0.900 | - | - | E1_COG1404 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D311719at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000204 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100362 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 6 | 5.720 | |||||