Protein Alignment DVL1 and Dvl1

DIOPT Version :10

• Sequence 1: NP_001317240.1
• Gene: DVL1 / 1855
• HGNCID: 3084
• Length: 695
• Species: Homo sapiens
• Sequence 2: NP_114008.1
• Gene: Dvl1 / 83721
• RGDID: 620632
• Length: 695
• Species: Rattus norvegicus
• Alignment Length: 696
• Identity: 661/696 - (94%)
• Similarity: 675/696 - (96%)
• Gaps: 2/696 - (0%)

Human     1 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFD 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFD 65

Human    66 DNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDG 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 DNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDG 130

Human   131 MDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSD 195
            |||||||||||||||||||||||:|||||||||||||||::|||||||||.||||||||||:|||
  Rat   131 MDNETGTESMVSHRRERARRRNRDEAARTNGHPRGDRRRELGLPPDSASTVLSSELESSSFIDSD 195

Human   196 EDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHH 260
            |:.:|||||||||||||||||||||.|||||||||.||||||||||||||||||:||||||||||
  Rat   196 EEDNTSRLSSSTEQSTSSRLIRKHKCRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHH 260

Human   261 FLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIV 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 FLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIV 325

Human   326 SQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTS 390
            |||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||:||||
  Rat   326 SQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAITRTS 390

Human   391 SSSLTSSVPGAPQLEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLY 455
            |||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||
  Rat   391 SSSLTSSVPGAPQLEEAPLTVKSDMSAIVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLY 455

Human   456 THVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQD 520
            ||||||||||||||||||:|||||||||||||||||||||||||||||||:|||||||||.||||
  Rat   456 THVEGFKERREARKYASSMLKHGFLRHTVNKITFSEQCYYVFGDLCSNLASLNLNSGSSGASDQD 520

Human   521 TLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRA 585
            ||||||||:.||||||||||||||||||||||||||||||||||.|||||||||||||||||.|.
  Rat   521 TLAPLPHPSVPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSAGSQQSEGSKSSGSTRSSHRT 585

Human   586 PGREKERRAAGAGGSGSESDHTAPSGVGSS-WRERPAGQLSRGSSPRSQASATAPGLPPPHPTTK 649
            |||| ||||.||||||||||||.|||.||: |.|||..||||||||||||||.||||||.||.||
  Rat   586 PGRE-ERRATGAGGSGSESDHTVPSGSGSTGWWERPVSQLSRGSSPRSQASAVAPGLPPLHPLTK 649

Human   650 AYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM 695
            ||.|||||||||||||||||||||||||||||||||||||||||||
  Rat   650 AYAVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DVL1	NP_001317240.1	DAX	1..85	CDD:197474	83/83 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..237		137/147 (93%)
		Dishevelled	90..247	CDD:460544	146/156 (94%)
		PDZ_Dishevelled-like	251..337	CDD:467201	85/85 (100%)
		DEP_dishevelled	417..499	CDD:239885	79/81 (98%)
		Dsh_C	503..685	CDD:463531	162/182 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..667		108/124 (87%)
Dvl1	NP_114008.1	DAX	1..85	CDD:197474	83/83 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..236		136/146 (93%)
		Dishevelled	90..247	CDD:460544	146/156 (94%)
		PDZ_Dishevelled-like	251..337	CDD:467201	85/85 (100%)
		DEP_dishevelled	417..499	CDD:239885	79/81 (98%)
		Dsh_C	503..685	CDD:463531	162/182 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	551..641		77/90 (86%)