Protein Alignment DVL1 and Dvl1

DIOPT Version :10

• Sequence 1: NP_001317240.1
• Gene: DVL1 / 1855
• HGNCID: 3084
• Length: 695
• Species: Homo sapiens
• Sequence 2: XP_006538581.1
• Gene: Dvl1 / 13542
• MGIID: 94941
• Length: 709
• Species: Mus musculus
• Alignment Length: 710
• Identity: 659/710 - (92%)
• Similarity: 674/710 - (94%)
• Gaps: 16/710 - (2%)

Human     1 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFD 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFD 65

Human    66 DNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDG 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 DNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDG 130

Human   131 MDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSD 195
            |||||||||||||||||||||||:||||||||||||||||:|||||||||.||||||||||:|||
Mouse   131 MDNETGTESMVSHRRERARRRNRDEAARTNGHPRGDRRRDLGLPPDSASTVLSSELESSSFIDSD 195

Human   196 EDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHH 260
            |:.:||||||||||||||||:||||.|||||||||.||||||||||||||||||:||||||||||
Mouse   196 EEDNTSRLSSSTEQSTSSRLVRKHKCRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHH 260

Human   261 FLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIV 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 FLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIV 325

Human   326 SQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTS 390
            |||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||:||||
Mouse   326 SQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAITRTS 390

Human   391 SSSLTSSVPGAP--------------QLEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITI 441
            ||||||||||||              :||||||||||||||:|||||||||||||||||||||||
Mouse   391 SSSLTSSVPGAPRSRCEPGLREVCSAELEEAPLTVKSDMSAIVRVMQLPDSGLEIRDRMWLKITI 455

Human   442 ANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLAT 506
            ||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||:
Mouse   456 ANAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGFLRHTVNKITFSEQCYYVFGDLCSNLAS 520

Human   507 LNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSE 571
            |||||||||.||||||||||||:.|||||||||||||||||||||||||||||.||||.||||||
Mouse   521 LNLNSGSSGASDQDTLAPLPHPSVPWPLGQGYPYQYPGPPPCFPPAYQDPGFSCGSGSAGSQQSE 585

Human   572 GSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSS-WRERPAGQLSRGSSPRSQAS 635
            |||||||||||.|.|||| ||||.||||||||||||.|||.||: |.|||..|||||||||||||
Mouse   586 GSKSSGSTRSSHRTPGRE-ERRATGAGGSGSESDHTVPSGSGSTGWWERPVSQLSRGSSPRSQAS 649

Human   636 ATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM 695
            |.||||||.||.||||.|||||||||||||||||||||||||||||||||||||||||||
Mouse   650 AVAPGLPPLHPLTKAYAVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DVL1	NP_001317240.1	DAX	1..85	CDD:197474	83/83 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..237		137/147 (93%)
		Dishevelled	90..247	CDD:460544	146/156 (94%)
		PDZ_Dishevelled-like	251..337	CDD:467201	85/85 (100%)
		DEP_dishevelled	417..499	CDD:239885	79/81 (98%)
		Dsh_C	503..685	CDD:463531	161/182 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..667		107/124 (86%)
Dvl1	XP_006538581.1	DAX	1..85	CDD:197474	83/83 (100%)
		Dishevelled	90..247	CDD:460544	146/156 (94%)
		PDZ_Dishevelled-like	251..337	CDD:467201	85/85 (100%)
		DEP_dishevelled	431..513	CDD:239885	79/81 (98%)
		Dsh_C	517..699	CDD:463531	161/182 (88%)