DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DUSP9 and CG10089

DIOPT Version :9

Sequence 1:	XP_011529425.1	Gene:	DUSP9 / 1852	HGNCID:	3076	Length:	415	Species:	Homo sapiens
Sequence 2:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster

Alignment Length:	148	Identity:	58/148 - (39%)
Similarity:	85/148 - (57%)	Gaps:	11/148 - (7%)

- Green bases have known domain annotations that are detailed below.

Human   237 QILPNLYLGSARDSANLESLAKLGIRYILNV--TPN--LPNFFEKNGDFHYKQIPISDHWSQNLS 297
            ::||.||:|:.|||.:...|.:..|.:|:.:  :|.  ||       |.||..:..||...||||
  Fly     7 KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLP-------DKHYLCVMASDTPDQNLS 64

Human   298 RFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNF 362
            ::|....:||..|..:...||:|||||:||||||.|||:|...||:..:|..:|:..::..:||.
  Fly    65 QYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNA 129

Human   363 NFMGQLLDFERSLRLEER 380
            .|..||.:||:....|||
  Fly   130 GFQSQLQEFEQFKLSEER 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DUSP9	XP_011529425.1	DSP_MapKP	38..169	CDD:238723
		CDC14	224..373	CDD:225297	54/139 (39%)
		DSPc	235..372	CDD:238073	53/138 (38%)
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	53/138 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1042
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.950