Protein Alignment Pax6 and sv

DIOPT Version :9

• Sequence 1: NP_001231127.1
• Gene: Pax6 / 18508
• MGIID: 97490
• Length: 436
• Species: Mus musculus
• Sequence 2: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 176/639 - (27%)
• Similarity: 249/639 - (38%)
• Gaps: 248/639 - (38%)

Mouse     3 NSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNENVSNGCV 67
            :.|.|||||||||||||||||..||:||||||:|.|||||||.|:              ||:|||
  Fly   174 DGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLR--------------VSHGCV 224

Mouse    68 SKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIP 132
            ||||.|||||||.:...||||||:||||.||..||.||||.|::||||||||||:|.:|:.||:|
  Fly   225 SKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVP 289

Mouse   133 SVSSINRVLRNLASEK-------------QQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPG 184
            |||||||::||.|:||             |.:|  |.:.....::..||:.|.          |.
  Fly   290 SVSSINRIVRNKAAEKAKHVHHHQQHHVSQSLG--GGHIATESVDSSTGTIGE----------PQ 342

Mouse   185 QPTQDGCQQQEGGGENTN---------SISSNGEDSDEAQM---------RLQLKRKLQRNRTSF 231
            .||.:    ......|||         ||.::|.||.:..:         ...:....::..|.:
  Fly   343 PPTSN----SSANSVNTNVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGY 403

Mouse   232 T---------------------------------QEQIEALEKEFERTHYP--DVFARERLAAKI 261
            :                                 :::|||.::..:...:.  |...|:|::. .
  Fly   404 SINGILGIQHGHHSHNNNNNSSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMST-Y 467

Mouse   262 DLPEARIQVWFSNRRAKW--RREEKLRNQ--------------RRQASNTPSHIPISSSFST--- 307
            ...:....:|    ..||  :.:.||..:              ..:|||..|..|||.|.:|
  Fly   468 SGDQLYTNIW----SGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASG 528

Mouse   308 ------------------SVYQPI--PQ-------PTTPVS------------------------ 321
                              |:|.|.  |.       |..|:|
  Fly   529 NDTSMLYDSITTISQTQSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALA 593

Mouse   322 ---SFTSGSMLGRTDTALTNTYSALPP--------------MPSFTMANNLPMQPPVPSQTSSYS 369
               ::||.:.|....:.:...:..:|.              :|..|..|:..::.|:   |:|..
  Fly   594 FDGNYTSMTSLENCSSLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKEPL---TNSDG 655

Mouse   370 CMLPTS----PSVNGRSYDTYTPPHM------------------QTHMNS----QPMGTSG---- 404
            |....:    .|.:.:|.|....||:                  .||.:|    ||.|.|.
  Fly   656 CSEDNNKEPEKSNSSQSSDHIASPHLHHIGEEQLRGNRRSNLNASTHPSSLIPLQPSGGSSLLNI 720

Mouse   405 -------------TTSTGLISPGVSVP----------VQVPGSE----PDMSQY 431
                         :.:.||.|....:|          ..||||:    |..:||
  Fly   721 NPSENRSDVELNLSNNVGLYSTPTVLPSFNHYSAGCSSVVPGSDYAYNPAYTQY 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pax6	NP_001231127.1	PAX	4..142	CDD:128645	92/137 (67%)
		Homeobox	228..281	CDD:395001	10/89 (11%)
sv	NP_524633.3	PAX	175..299	CDD:128645	92/137 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910